Skeletal muscle wasting

Critically ill patients frequently suffer muscle weakness whilst in critical care. Ultrasound can reliably track loss of muscle size, but also quantifies the arrangement of the muscle fascicles, known as the muscle architecture. We sought to measure both pennation angle and fascicle length, as well as tracking changes in muscle thickness in a population of critically ill patients.

8p viottohahn 30-03-2022 7 1   Download

Whole-body vibration has been suggested for the prevention of muscle mass loss and muscle wasting as an attractive measure for disuse atrophy. This study examined the effects of daily intermittent whole-body vibration and weight bearing during hindlimb suspension on capillary number and muscle atrophy in rat skeletal muscles.

9p viannito2711 20-04-2021 14 1   Download

Evidence from cachectic cancer patients and animal models of cancer cachexia supports the involvement of Forkhead box O (FoxO) transcription factors in driving cancer-induced skeletal muscle wasting. However, the genome-wide gene networks and associated biological processes regulated by FoxO during cancer cachexia are unknown.

17p vialabama2711 21-09-2020 7 1   Download

Cachexia is a multi-factorial, systemic syndrome that especially affects patients with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival and quality of life. The most important clinical feature of cachexia is the excessive wasting of skeletal muscle mass.

14p vinaypyidaw2711 26-08-2020 10 2   Download

Physical exercise and nutritional treatment are promising measures to prevent muscle wasting that is frequently observed in advanced-stage cancer patients. However, conventional exercise is not always suitable for these patients due to physical weakness and therapeutic side effects.

17p vimanila2711 25-06-2020 10 1   Download

In an attempt to identify potential therapeutic targets for the correction of muscle wasting, the gene expression of several pivotal proteins involved in protein metabolism was investigated in experimental atrophy induced by transient or definitive denervation, as well as in four animal models of muscular dystrophies (deficient for calpain 3, dysferlin,a-sarcoglycan and dystrophin, respectively).

16p vinaphone15 27-02-2013 40 1   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P48. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 59 5   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P47. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 111 3   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P46. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 52 4   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P45. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 50 3   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P44. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 40 4   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P43. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 53 4   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P42. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 47 4   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P41. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 50 3   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P40. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 45 3   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P39. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 54 4   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P38. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 42 3   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P37. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 37 3   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P36. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 42 4   Download

Sarcopenia Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments P35. Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. ...

10p pretty27 10-12-2010 52 4   Download