Skin and mucosal effects

With increasing numbers of patients with unresectable locoregionally advanced (LA) head and neck squamous cell carcinoma (HNSCC) receiving cetuximab/radiotherapy (RT), several guidelines on the early detection and management of skin-related toxicities have been developed.

13p vinaypyidaw2711 26-08-2020 17 2   Download

Disinfectants and mixtures of these. Minimal contact times should be at least 15 s on skin areas with few sebaceous glands and at least 10 min on sebaceous gland-rich ones. Mucosal disinfection: Germ counts can be reduced by PVP iodine or chlorhexidine (contact time 2 min), although not as effectively as on skin. Wound disinfection can be achieved with hydrogen peroxide (0.3%–1% solution; short, foaming action on contact with blood and thus wound cleansing) or with potassium permanganate (0.0015% solution, slightly astringent), as well as PVP iodine, chlorhexidine, and biguanidines.

16p bigbaby87 04-09-2010 102 11   Download