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Small subunit
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Accumulating evidence indicates that aberrant non-SMC condensin II complex subunit D3 (NCAPD3) is associated with carcinogenesis of various cancers. Nevertheless, the biological role of NCAPD3 in the pathogenesis of non-small cell lung cancer (NSCLC) remains unclear.
12p
vishanshan
27-06-2024
1
1
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This study aims to compare microRNA expression levels in wt and Bag-1 knockout (KO) MCF-7 breast cancer cells. hsa-miR-429 was selected as a potential miRNA in BAG-1KO MCF-7 cells because of the downregulation both in bioinformatics and validation qRT-PCR assay. According to predicted mRNA targets and functional enrichment analysis the ten hub proteins that are phosphatidylinositol4,5-biphosphate 3-kinase catalytic subunit alpha (PIK3CA), kinase insert domain receptor (KDR), GRB2 associated binding protein 1 (GAB1).
30p
lyhuyenthu
31-01-2023
2
2
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Emerging evidence has proven the robust role of tumor mutation burden (TMB) and immune cell infltration (ICI) in cancer immunotherapy. However, the precise efect of TMB and ICI on clear cell renal cell carcinoma (ccRCC) remains elusive and merits further investigation.
14p
vihagrid
30-01-2023
12
3
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Ribosomal protein S6 (S6), a downstream efect media of the AKT/mTOR pathway, not only is a part of 40S small subunit of eukaryotic ribosome, but also involves in protein synthesis and cell proliferation during cancer development.
11p
visusanwojcicki
28-06-2022
4
2
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The phylogenetic relationship of 83 taxa of Santalaceae s.l. was reconstructed based on the molecular data sets including the nuclear ribosomal (small and large subunit rDNA) and the chloroplast rbcL, matK, and trnL-F regions. The Maximum likelihood (ML) and Bayesian inference (BI) methods were used to build the phylogenetic trees.
8p
viellenkullman
13-05-2022
6
1
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Exploring the phylogenetic relationships between taxa provides important information for science. The phylogenetic study of Macrosolen was conducted based on molecular data sets of 27 taxa with five DNA regions including chloroplast rbcL, matK, and trnL-F and nuclear ribosomal (small subunit rDNA and large subunit rDNA) regions to reconstruct the phylogenetic relationship of Macrosolen.
7p
viginnirometty
04-05-2022
17
1
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Chaetognaths (arrow worms) are an enigmatic group of transparent planktonic invertebrates and play an important role in the marine food web. Their morphological and developmental features have raised extensive debates since the discovery of the phylum in the 18th century. Uncertainty in the phylogenetic placement of certain chaetognath species still exists and is puzzling many scientists who have tried to clarify this task.
11p
dolomite36
30-12-2021
9
1
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Eriophyoid mites are recognized as the second most economically important group among the Acari following spider mites. The identification of eriopyhoid mites traditionally based on morphological characters. However, the size of these diagnostic structures is very small and this often causes misidentification of species. In this study, we used DNA-based identification for five eriophyoid species collected from the Thrace region of Turkey (Aceria erinea, Rhyncaphytoptus ficifoliae, Eriophyes pyri, Aceria massalongoi, Colomerus vitis collected from Juglans regia L., Ficus carica L.
7p
dolomite36
30-12-2021
12
0
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Pluteus and Volvopluteus are two closely related genera of Pluteaceae that comprise saprotrophic fungi. Although the genera have been well-studied in Europe and North and South America, the diversity of Pluteus, mainly Pluteus sect. Pluteus, and Volvopluteus in Turkey is poorly known due to insufficient morphological descriptions and a lack of DNA sequence data. In this study, the diversity of Pluteus sect. Pluteus and Volvopluteus in Turkey is evaluated by employing both morphological features and phylogenetic approaches. A general phylogeny of Pluteus sect.
19p
tudichquannguyet
29-11-2021
8
1
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Inferring phylogenetic trees for newly recovered genomes from metagenomic samples is very useful in determining the identities of uncultivated microorganisms. Even though 16S ribosomal RNA small subunit genes have been established as “gold standard” markers for inferring phylogenetic trees, they usually cannot be assembled very well in metagenomes due to shared regions among 16S genes. Using single-copy marker genes to build genome trees has become increasingly popular for uncultivated species.
10p
vilarryellison
29-10-2021
9
1
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Recently, analysis of bone from knockout mice identified muscarinic acetylcholine receptor subtype M3 (mAChR M3) and nicotinic acetylcholine receptor (nAChR) subunit α2 as positive regulator of bone mass accrual whereas of male mice deficient for α7-nAChR (α7KO) did not reveal impact in regulation of bone remodeling.
12p
vianttinic2711
20-04-2021
22
3
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Total DNA of the anabas specimens (A1, A2, A3, A4) in Vietnam were extracted using PHUSA-IHHNV kit and according to the process of Phu Sa Biochemical Company. The mitochondrial cytochrome oxidase subunit I (COI) gene were amplified using PCR reaction. The obtained PCR products were checked using 2 % agarose gel electrophoresis and were sequenced with both the forward and reverse primers using an automated sequencer ABI 3730XL of Applied Biosystems by Sangers method. The genetic distances (Dij ) between the anabas species in Vietnam (A1, A2, A3, A4) are very small from 0.0046 to 0.
9p
trinhthamhodang9
10-12-2020
15
2
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Ribonucleotide reductase (RR) is an essential enzyme involved in DNA synthesis. We hypothesized that RR subunit M2 (RRM2) might be a novel prognostic and predictive biomarker for estrogen receptor (ER)-negative breast cancers.
16p
vilisa271
22-09-2020
11
1
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SUMOylation, an important post-translational modification, associates with the development of hepatocellular carcinoma (HCC). p65, one of the most important subunits of NF-κB, is a key regulator in the development of HCC and has been reported to be SUMOylated by exogenous small ubiquitin-related modifier 3 (SUMO3) in HEK 293T cells.
14p
vimoscow2711
29-08-2020
10
1
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This study aimmed to evaluate the expression of p53-inducible RR small subunit 2 homologue (p53R2) in Lung sarcomatoid carcinoma (LSC) and its association with clinicopathological parameters and prognosis.
7p
vibaku2711
22-07-2020
14
2
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Peste-des-petits Ruminants (PPR) is a disease of small ruminants especially goat and its control and eradication till 2030 wants an extensive research to develop a potent vaccine. The role of surface HN protein in the attachment of the virus to cellular receptors makes it an appropriate target to develop a theranostics against the virus. In this study, cytotoxic T cells epitopes that will bind to MHC class I alleles were predicted out using bioinformatic tools.
8p
trinhthamhodang1212
06-04-2020
12
1
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Most isolates of the genus Trichoderma were found to act as mycoparasites of many economically important aerial and soil-borne plant pathogens. Trichoderma has gained importance as a substitute for chemical pesticides and hence an attempt was intended to corroborate the positive relatedness of molecular and morphological characters. Fungal strains of Trichoderma BSAs were isolated collected from four different districts of Uttar Pradesh, India. The universal primers were used for amplification of 5.8SrRNA gene fragment and the strain was characterized by using 5.
9p
cothumenhmong1
11-12-2019
9
0
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A new rock-inhabiting fungal taxon was isolated from St. Margarethen Church in Vienna, Austria. Based on small subunit and internal transcribed regions of rDNA sequencing, the new taxon was described as Capnobotryella isiloglui Sert & Sterflinger.
7p
vi4mua
24-02-2019
12
1
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In vitro culture systems were used to assess the growth inhibition of kinetoplastids by a variety of aminoglycosides. The parasites were allowed to grow to the stationary phase in the presence of varying concentrations of the drugs. The IC-50 for every drug was calculated by comparison with the control.
8p
vitamix
15-02-2019
15
0
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The Brittle 2 (Bt2) gene encodes a small subunit of ADP-glucose pyrophosphorylase (AGPase) enzyme, one of the enzymes that play an important role in endosperm starch biosynthesis.
7p
sony2711
28-01-2019
19
2
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