Solid tumors

The aim of this study is to (1) Describe the ultrasound characteristics of ovarian tumors according to the O-RADS classification. (2) Investigate the signs predicting malignancy in the O-RADS 3, 4, and 5 categories.

7p viengfa 23-10-2024 0 0   Download

Solid pseudopapillary tumors (SPTs) of the pancreas is a low-grade malignant tumor, accounting for only 1–2.5% of all pancreatic tumors. In particular, small (≤ 3 cm) SPTs do not often have typical computed tomography (CT) features, making them easily misdiagnosed with other solid tumors and eventually affecting the choice of treatment method.

5p viling 11-10-2024 0 0   Download

To evaluate the surgical outcomes of solid pseudopapillary neoplasms (SPNs) of the pancreas in children at the Vietnam National Children's Hospital. Methods: This study was a descriptive case series that retrospectively analyzed 26 patients diagnosed with pancreatic SPNs who underwent surgical treatment at the National Children's Hospital between January 2021 and May 2024.

8p vibecca 01-10-2024 5 2   Download

Khối u đặc giả nhú (Solid pseudopapillary tumor - SPT) của tuyến tụy là một khối u hiếm gặp, thường có đặc trưng là một khối có vỏ bao bọc tốt, với khả năng ác tính thấp. Bài viết trình bày một bài báo cáo khác thường về SPT ở một phụ nữ tuổi trung niên với diễn biến lâm sàng lành tính.

8p viavatis 05-08-2024 4 2   Download

Currently, no available coherent management protocol exists for pediatric cancers associated with pleural effusion, ascites, and pericardial efusion. This study aimed to retrospectively present our experience in treating pediatric cancer patients with pleural effusion, ascites, and pericardial efusion using interleukin-2 (IL-2) and dexa‑ methasone (DEX) intracavitary injections.

8p vielonmusk 21-01-2022 10 0   Download

Cisplatin (CP) is considered one of the most effective and widely used anti-neoplastic drug in the treatment of different solid organ tumors. The present study was carried out to assess the hematological changes following CP administration in Wistar albino rats and its amelioration by extract of Andrographis paniculata (AP). The study included 60 Wistar albino rats were divided into 12 rats in each group. Group I served as normal control group.

8p angicungduoc6 22-07-2020 8 1   Download

AR-42, a new orally bioavailable, potent, hydroxamate-tethered phenylbutyrate class I/IIB histone deacetylase inhibitor currently is under evaluation in phase 1 and 2 clinical trials and has demonstrated activity in both hematologic and solid tumor malignancies. This report focuses on the preclinical characterization of the pharmacokinetics of AR-42 in mice and rats.

9p caothientrangnguyen 09-05-2020 18 3   Download

Amplification of N-myc oncogene is a frequent event in advanced stages of human neuroblastoma and correlates with poor prognosis and enhanced neovascularization. Angiogenesis is an indispensable prerequisite for the progression and metastasis of solid malignancies, which is modulated by tumor suppressors and oncogenes. We have addressed the possibility that N-myc oncogene might regulate angiogenesis in neuroblastoma. Here, we report that experimental N-Myc overexpression results in down-regulation of leukemia inhibitory factor (LIF), a modulator of endothelial cell proliferation....

10p system191 01-06-2013 34 4   Download

The multisubstrate nucleoside kinase of Drosophila melanogaster(Dm-dNK) can be expressed in human solid tumor cells and its unique enzymatic properties makes this enzyme a suicide gene candidate. In the present study,Dm-dNK was stably expressed in the CCRF-CEM and H9 T-lymphoblastoid cell lines. The expressed enzyme was localized to the cell nucleus and the enzyme retained its activity.

11p fptmusic 11-04-2013 41 2   Download

The introduction of noncanonical amino acids and bio-physical probes into peptides and proteins, and total or segmental isotopic labelling has the potential to greatly aid thedeterminationofproteinstructure, functionandprotein– protein interactions.To obtain a peptide as large as possible by solid-phase peptide synthesis, native chemical ligation was introduced to enable synthesis of proteins of up to 120 amino acids in length.

15p dell39 03-04-2013 42 4   Download

Aberrant differentiation is a characteristic feature of neoplastic transforma-tion, while hypoxia in solid tumors is believed to be linked to aggressive behavior and poor prognosis. However, the possible relationship between hypoxia and differentiation in malignancies remains poorly defined.

14p vinaphone15 27-02-2013 36 1   Download

Formation of new blood vessels is required for the growth and metastasis of all solid tumors. New blood vessels are established in tumors mainly through angiogenesis. Brain tumors in particular are highly angiogenic. Therefore, interventions designed to prevent angiogenesis may be effective at controlling brain tumors.

12p vinaphone15 25-02-2013 48 3   Download

Protein oligomeric complexes have emerged as a major target of current research because of their key role in aggregation processes in living systems andin vitro. Hydrophobic and charged surfaces may favour the self-assembly process by recruiting proteins and modifying their interactions. We found that equine lysozyme assembles into multimeric complexes with oleic acid (ELOA) at the solid–liquid interface within an ion-exchange chromatography column preconditioned with oleic acid.

15p vinaphone15 25-02-2013 51 4   Download

The expression of proteoglycans (PGs), essential macromolecules of the tumor microenvironment, is markedly altered during malignant transforma-tion and tumor progression. Synthesis of stromal PGs is affected by factors secreted by cancer cells and the unique tumor-modified extracellular matrix may either facilitate or counteract the growth of solid tumors.

20p viettel02 19-02-2013 52 4   Download

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors

13p dauphong3 03-01-2012 56 6   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hematemesis, a very rare presentation of solid pseudo-papillary tumors of the pancreas: a case report

3p dauphong1 21-12-2011 55 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A solid pseudopapillary tumor of the pancreas treated with laparoscopic distal pancreatectomy and splenectomy: a case report and review of the literature

4p toshiba25 09-12-2011 59 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors...

7p thulanh25 06-12-2011 50 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Brain metastases from solid tumors: disease outcome according to type of treatment and therapeutic resources of the treating center

7p toshiba22 21-11-2011 45 4   Download

Abstract Resistance to conventional anticancer therapies in patients with advanced solid tumors has prompted the need of alternative cancer therapies. Moreover, the success of novel cancer therapies depends on their selectivity for cancer cells with limited toxicity to normal tissues. Several decades after Coley's work a variety of natural and genetically modified non-pathogenic bacterial species are being explored as potential antitumor agents, either to provide direct tumoricidal effects or to deliver tumoricidal molecules.

9p toshiba23 18-11-2011 59 2   Download