Specific metabolic pathways
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Ebook "Metabolism in cancer" presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field.
272p cotieubac1004 15-03-2024 2 0 Download
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Ebook "AMPK: Methods and protocols" explores the latest methods used to study AMPK by computational, biochemical, biophysical, cellular, and ex vivo and in vivo approaches. The chapters in this book cover specific topics, such as methods to measure change in cellular energy metabolism and analyze metabolic pathways regulated by AMPK; bioinformatics tools to identify AMPK targets; knockdown of AMPK by CRISPR-Cas9;...
617p lucchinguyen 28-12-2023 4 2 Download
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Adipose tissues (ATs), including visceral ATs (VATs) and subcutaneous ATs (SATs), are crucial for maintaining energy and metabolic homeostasis. SATs have been found to be closely related to obesity and obesityinduced metabolic disease. Some studies have shown a significant association between subcutaneous fat metabolism and sexes.
13p vihagrid 30-01-2023 6 3 Download
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The succession of the gut microbiota during the first few years plays a vital role in human development. We elucidate the characteristics and alternations of the infant gut microbiota to better understand the correlation between infant health and microbiota maturation.
21p viarchimedes 26-01-2022 11 0 Download
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The cattle gastrointestinal tract (GIT) is the main enterohemorrhagic Escherichia coli (EHEC) reservoir. In order to identify nutrients required for the survival or multiplication of EHEC in the bovine GIT, we compared the transcriptomes of the EHEC O157:H7 reference strain EDL933 cultured in vitro in bovine digestive contents (DCs) (rumen, small intestine and rectum) using RNA-sequencing.
19p vitzuyu2711 29-09-2021 8 1 Download
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Cytoplasmic male sterility (CMS) has been widely used for commercial F1 hybrid seeds production. CMS is primarily caused by chimeric genes in mitochondrial genomes. However, which specific stages of anther development in cabbage are affected by the chimeric genes remain unclear.
15p vitzuyu2711 29-09-2021 16 1 Download
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The fasting-refeeding perturbation has been used extensively to reveal specific genes and metabolic pathways that control energy metabolism in the chicken. Most global transcriptional scans of the fasting-refeeding response in liver have focused on juvenile chickens that were 1, 2 or 4 weeks old.
34p vijeeni2711 24-07-2021 11 0 Download
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Mass spectrometric analysis of microbial metabolism provides a long list of possible compounds. Restricting the identification of the possible compounds to those produced by the specific organism would benefit the identification process.
13p vikentucky2711 26-11-2020 8 1 Download
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Obesity-induced chronic inflammation plays a fundamental role in the pathogenesis of metabolic syndrome (MS). Recently, a growing body of evidence supports that miRNAs are largely dysregulated in obesity and that specific miRNAs regulate obesity-associated inflammation.
7p vikentucky2711 24-11-2020 17 1 Download
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Knockout strategies, particularly the concept of constrained minimal cut sets (cMCSs), are an important part of the arsenal of tools used in manipulating metabolic networks. Given a specific design, cMCSs can be calculated even in genome-scale networks.
9p vioklahoma2711 19-11-2020 13 1 Download
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Many biological pathways have been created to represent different types of knowledge, such as genetic interactions, metabolic reactions, and gene-regulating and physical-binding relationships. Biologists are using a wide range of omics data to elaborately construct various context-specific differential molecular networks.
9p viflorida2711 30-10-2020 17 2 Download
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In the ethno-pharmacological approach, local knowledge about the potential uses of the plants is very useful as compared to the random approach where indigenous knowledge is not taken into consideration. Phytochemicals produced in plants are secondary compounds responsible for metabolic activities and defense in purpose. Phytochemicals are produced by specific biochemical pathways, which occur inside the plant cells.
9p angicungduoc6 20-07-2020 12 2 Download
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Using a pathway-focused approach, we aimed to provide a subgroup-specific basis for finding novel therapeutic strategies and further refinement of the risk stratification in pediatric medulloblastoma.
15p vikuala271 13-06-2020 8 0 Download
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Korean pine seeds have primary dormancy following dispersal, leading to poor seed germination and seedling establishment. Metabolic homeostasis determines whether the seeds are dormant or non-dormant. However, the specific metabolic pathways that maintain the primary dormancy of pine seeds are poorly understood.
15p viharuno2711 21-04-2020 9 1 Download
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Deoxyxylulose 5-phosphate synthase (DXS) and deoxyxylulose 5-phosphate reductoisomerase (DXR) are the enzymes that catalyze the first two enzyme steps of the methylerythritol 4-phosphate (MEP) pathway to supply the isoprene building-blocks of carotenoids.
16p viuchiha2711 21-04-2020 5 1 Download
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An industrial clavulanic acid (CA) overproducer Streptomyces clavuligerus strain, namely DEPA, was engineered to further enhance its CA production. Single or multiple copies of ccaR, claR (pathway-specific activators), and cas2 (CA synthase) genes under the control of different promoters were introduced into this strain.
15p nutifooddau 27-01-2019 20 2 Download
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Agriculture and forestry are poised on the brink of a quantum leap forward through the further application of exciting new tools such as genomics and transgenic plants. In the near future, it will be possible to produce a higher quantity of improved quality crops than even imagined just a few years ago. In addition to feed and food, it will be possible to provide raw materials for industrial uses. For example, cotton fibers, wood ligno-celluloses, corn carbohydrates, soybean oils, and other plant constituents will be altered via designed changes in metabolic pathways.
17p loixinloi 08-05-2013 58 3 Download
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Agriculture and forestry are poised on the brink of a quantum leap forward through the further application of exciting new tools such as genomics and transgenic plants. In the near future, it will be possible to produce a higher quantity of improved quality crops than even imagined just a few years ago. In addition to feed and food, it will be possible to provide raw materials for industrial uses. For example, cotton fibers, wood ligno-celluloses, corn carbohydrates, soybean oils, and other plant constituents will be altered via designed changes in metabolic pathways.
102p loixinloi 08-05-2013 56 10 Download
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Spontaneous oxidation of 3-hydroxykynureine (3-HK), a metabolic inter-mediate of the tryptophan degradation pathway, elicits a remarkable oxida-tive stress response in animal tissues. In the yellow fever mosquito Aedes aegyptithe excess of this toxic metabolic intermediate is efficiently removed by a specific 3-HK transaminase, which converts 3-HK into the more sta-ble compound xanthurenic acid.
10p fptmusic 12-04-2013 35 1 Download
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14-3-3 proteins belong to a family of conserved molecules expressed in all eukaryotic cells, which play an important role in a multitude of signaling pathways. 14-3-3 proteins bind to phosphoserine⁄phosphothreonine motifs in a sequence-specific manner. More than 200 14-3-3 binding partners have been found that are involved in cell cycle regulation, apoptosis, stress responses, cell metabolism and malignant transformation.
9p dell39 27-03-2013 39 2 Download