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Báo cáo khoa học: Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase
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Spontaneous oxidation of 3-hydroxykynureine (3-HK), a metabolic inter-mediate of the tryptophan degradation pathway, elicits a remarkable oxida-tive stress response in animal tissues. In the yellow fever mosquito Aedes aegyptithe excess of this toxic metabolic intermediate is efficiently removed by a specific 3-HK transaminase, which converts 3-HK into the more sta-ble compound xanthurenic acid.
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