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Specific pathology
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Ebook "Neural crest induction and differentiation" compile contributions by recognized leaders in the neural crest field who discuss all aspects of modem neural crest biology. From its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function.
267p
ladongphongthanh1008
22-04-2024
2
1
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Alzheimer’s disease (AD) is characterized by neuronal loss and astrocytosis in the cerebral cortex. However, the specific effects that pathological mutations and coding variants associated with AD have on the cellular composition of the brain are often ignored.
19p
vibransone
28-03-2024
3
2
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Cerebral amyloidosis, neuroinflammation, and tauopathy are key features of Alzheimer’s disease (AD), but interactions among these features remain poorly understood. Our previous multiscale molecular network models of AD revealed TYROBP as a key driver of an immune- and microglia-specific network that was robustly associated with AD pathophysiology.
20p
vibransone
28-03-2024
3
2
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Comprehensive mutational profiling data now available on all major cancers have led to proposals of novel molecular tumor classifications that modify or replace the established organ- and tissue-based tumor typing. The rationale behind such molecular reclassifications is that genetic alterations underlying cancer pathology predict response to therapy and may therefore offer a more precise view on cancer than histology.
17p
vibransone
28-03-2024
4
2
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The number of druggable tumor-specific molecular aberrations has grown substantially in the past decade, with a significant survival benefit obtained from biomarker matching therapies in several cancer types. Molecular pathology has therefore become fundamental not only to inform on tumor diagnosis and prognosis but also to drive therapeutic decisions in daily practice.
19p
vibransone
28-03-2024
2
2
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Systemic sclerosis (SSc) is a multi-organ autoimmune disease characterized by skin fibrosis. Internal organ involvement is heterogeneous. It is unknown whether disease mechanisms are common across all involved affected tissues or if each manifestation has a distinct underlying pathology.
24p
vioraclene
31-03-2024
6
2
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Renal cell carcinoma (RCC) is a heterogeneous disease comprising histologically defned subtypes. For therapy selection, precise subtype identification and individualized prognosis are mandatory, but currently limited. Our aim was to refne subtyping and outcome prediction across main subtypes, assuming that a tumor is composed of molecular features present in distinct pathological subtypes.
19p
viellison
28-03-2024
4
2
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The rapid advancement of single-cell transcriptomics in neurology has allowed for profiling of post-mortem human brain tissue across multiple diseases. Over the past 3 years, several studies have examined tissue from donors with and without diagnoses of Alzheimer’s disease, highlighting key changes in cell type composition and molecular signatures associated with pathology and, in some cases, cognitive decline.
13p
vicwell
29-02-2024
2
1
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Tumor and pseudotumor (TP) at the proximal femur (PF) can seriously affect mortality, extremity function, and body integrity. However, reports often focused on a specific tumor, not regional lesions. This study focuses on clinical findings, imaging, micro-pathology, and the treatment of all TP at the site.
7p
vikissinger
21-12-2023
3
1
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The pathological diagnosis and prognosis prediction of hepatocellular carcinoma (HCC) is challenging due to the lack of specific biomarkers. This study aimed to validate the diagnostic and prognostic efficiency of Kidney-type glutaminase (GLS1) for HCC in prospective cohorts with a large sample size.
12p
vileonardodavinci
23-12-2023
4
3
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Locally advanced non-small cell lung cancer (NSCLC) with N1/N2 lymph node metastasis is challenging with poor survival. Neo-adjuvant chemo-immunotherapy has gained benefits in a proportion of these patients. However no specific biomarker has been proved to predict the effect before therapy.
10p
vileonardodavinci
23-12-2023
8
3
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Previous assessments of peritumoral infammatory infltrate in colorectal cancer (CRC) have focused on the role of CD8+ T lymphocytes. We sought to compare the prognostic value of CD8 with downstream indicators of active immune cell function, specifically granzyme B (GZMB) and CD68 in the tumour microenvironment.
13p
vialfrednobel
23-12-2023
4
3
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Part 1 book "A toxicologist's guide to clinical pathology in animals" includes content: The fundamentals, hematology highlights, blood and urine sampling, species specifics, hematology diagnosis.
81p
oursky08
01-11-2023
4
1
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As an adult tumor with the most invasion and the highest mortality rate, the inherent heterogeneity of glioblastoma (GBM) is the main factor that causes treatment failure. Therefore, it is important to have a deeper understanding of the pathology of GBM. Some studies have shown that Eukaryotic Initiation Factor 4A-3 (EIF4A3) can promote the growth of many people’s tumors, and the role of specific molecules in GBM remains unclear.
12p
visharma
20-10-2023
2
2
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Primary breast diffuse large B-cell lymphoma (PB-DLBCL) is a rare localized extranodal lymphoma. It is mainly diagnosed by pathological examination due to the lack of specific clinical and imaging manifestations. The patient subsequently received comprehensive treatment based on six cycles of rituximab-cyclophosphamide, hydroxydaunomycin, oncovin, prednisone (R-CHOP) chemotherapy.
5p
viintuit
26-09-2023
3
0
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Part 2 book "Textbook of cosmetic dermatology" includes content: Cosmetology for non-pathological skin, cosmetology for specific locations and conditions, skin care for specific groups, cosmetological treatments, noninvasive assessment techniques
360p
oursky02
06-08-2023
8
2
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We implement 2 different multitask learning (MTL) techniques, hard parameter sharing and crossstitch, to train a word-level convolutional neural network (CNN) specifically designed for automatic extraction of cancer data from unstructured text in pathology reports.
10p
vighostrider
25-05-2023
3
2
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Elastofibroma dorsi is a rare benign tumor of soft tissue, typically under the lower angle of the scapula. Its specific location and distinctive clinical symptoms can provide enough information for diagnosis. Nevertheless, pathological confirmation by biopsy may be needed to rule out other malignancies.
5p
vigamora
23-05-2023
2
2
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Ectopic intrathyroidal thymic tissue in an adult patient: A case report and review of the literature
Ectopic intrathyroidal thymic tissue is a rare diagnosis, specifically in adults. Such ectopic tissue is usually misdiagnosed as benign or malignant thyroid lesions and is mainly investigated by ultrasonography and pathologic examination.
6p
vigamora
23-05-2023
5
2
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Suburbs in Melbourne present to us a unique context with which a new approach towards urban form can be devised using the existing conditions and opportunities found with infrastructural developments. This thesis contains the investigations on the various 'pathologies' of the urban fabric specifically on the potential use of 'Spaces Left-Over After Planning' as by-product to infrastructural development in relation to the reinvigoration of Melbourne suburbs under the influence of current and future metropolitan growth pressures.
98p
runthenight05
01-03-2023
6
2
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