Sphingolipids

Xem 1-5 trên 5 kết quả Sphingolipids

Báo cáo khoa học: P-Glycoprotein is localized in intermediate-density membrane microdomains distinct from classical lipid rafts and caveolar domains

P-glycoprotein (Pgp), a member of the ATP-binding cassette (ABC) super-family responsible for the ATP-driven extrusion of diverse hydrophobic molecules from cells, is a cause of multidrug resistance in human tumours. Pgp can also operate as a phospholipid and glycosphingolipid flippase, and has been functionally linked to cholesterol, suggesting that it might be associated with sphingolipid–cholesterol microdomains in cell membranes.

14p fptmusic 12-04-2013 30 3 Download

Báo cáo khoa học: Saposin B mobilizes lipids from cholesterol-poor and bis(monoacylglycero)phosphate-rich membranes at acidic pH

Sphingolipid activator proteins (SAPs), GM2 activator protein (GM2AP) and saposins (Saps) A–D are small, enzymatically inactive glycoproteins of the lysosome. Despite of their sequence homology, these lipid-binding and -transfer proteins show different specificities and varying modes of action. Water-soluble SAPs facilitate the degradation of membrane-bound glyco-sphingolipids with short oligosaccharide chains by exohydrolases at the membrane–water interface.

16p galaxyss3 19-03-2013 31 3 Download

Báo cáo khoa học: An X-ray diffraction study of model membrane raft structures

$Báo cáo khoa học: An X-ray diffraction study of model membrane raft structures$

Protein sorting and assembly in membrane biogenesis and function involves the creation of ordered domains of lipids known as membrane rafts. The rafts are comprised of all the major classes of lipids, including glycero-phospholipids, sphingolipids and sterol. Cholesterol is known to interact with sphingomyelin to form a liquid-ordered bilayer phase.

14p viettel02 19-02-2013 40 2 Download
Whey Products as Functional Foods

In the early 1980’s, the Japanese were the first to recognize dairy components as having significant contributions to “physiologically functional foods.” Since then there has been an increasing number of investigations that have supported this view.Current evidence for the health benefits of most dairy foods and dairy components is based primarily on in vitro and in vivo animal studies. Human clinical studies are still needed in many areas.

34p nhocbuonthich 18-06-2012 134 24 Download
Báo cáo y học: " Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: "Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift

20p toshiba17 28-10-2011 36 3 Download