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Stage II
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Rectal cancer treatment has transformed in recent years, with neoadjuvant treatment (NT) and total neoadjuvant treatment (TNT) aiming to enhance pathological responses. This pioneering study in our country delves into rectal cancer management, offering crucial insights by examining pathological outcomes in patients treated with the NT and TNT approach, shaping the evolving landscape.
9p
vishanshan
27-06-2024
1
1
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Perineural invasion (PNI) is the invasion of nerves by cancer cells and is associated with poor survival in stage II colorectal cancer. However, PNI can be further subdivided according to the depth of invasion, and the depth of PNI has not been clearly linked to prognosis.
8p
vishanshan
27-06-2024
1
1
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The clinical value and impact in patients with EGFR mutation on survival outcomes is further needed to be elucidated to decide whether the application of EGFR-TKIs was appropriate in early lung adenocarcinoma (LUAD) stage appearing as subsolid nodules.
9p
vishanshan
27-06-2024
4
1
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To establish a nomogram to predict the probability of survival of patients with stage II/III gastric cancer (GC) who received incomplete peri-operative adjuvant chemotherapy (PAC). The medical records of stage II/III GC patients who received curative resection and 1 to 5 cycles of PAC from two tertiary hospitals were retrospectively reviewed.
12p
vishanshan
27-06-2024
3
1
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The current standard of care in the neoadjuvant setting for high-risk HER2-positive (HER2+) breast cancer is to combine systemic chemotherapy with dual HER2 blockade, trastuzumab and pertuzumab. Targeted therapies have significantly improved outcomes for patients with HER2-positive breast cancer.
8p
vikoch
27-06-2024
1
1
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For high-risk stageIImismatch repair defcient (dMMR) colon cancers, the benefit of adjuvant chemo‑ therapy remains debatable. The principal aim of this study was to evaluate the prognostic value of high-risk factors and the effect of oxaliplatin-based adjuvant chemotherapy among dMMR stageIIcolon cancers.
9p
vikoch
27-06-2024
1
1
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presents the following content: Chapter I: to deliver you from the preliminary terrors; Chapter II: on different degrees of smallness; Chapter III: on relative growings; Chapter IV: simplest cases; Chapter V: next stage: what to do with constants; Chapter VI: sums, differences, products, and quotients; Chapter VII: successive differentiation; Chapter VIII: when time varies; Chapter IX: introducing a useful dodge; Chapter X: geometrical meaning of differentiation;…
296p
zizaybay1103
29-05-2024
4
2
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Ebook "Introduction to computational biology: An evolutionary approach" Analysis of molecular sequence data is the main subject of this introduction to computational biology. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models.
329p
tracanhphuonghoa1007
22-04-2024
8
2
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Assessment of the unwanted effects of concurrent chemoradiotherapy for nasopharyngeal carcinoma. Subjects and methods: A retrospective combined prospective study and description of 53 patients with stage II-IVA nasopharyngeal carcinoma, treated with concurrent chemoradiotherapy by the cisplatin regimen on days 1, 22 and 43 at the National Otorhinolaryngology Hospital of Vietnam from 2019 to 2023.
5p
viohoyo
02-04-2024
4
1
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Cancer recurrence after tumor resection in early-stage non-small cell lung cancer (NSCLC) is common, yet difficult to predict. The lung microbiota and systemic immunity may be important modulators of risk for lung cancer recurrence, yet biomarkers from the lung microbiome and peripheral immune environment are understudied. Such markers may hold promise for prediction as well as improved etiologic understanding of lung cancer recurrence.
17p
viellison
28-03-2024
2
1
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Dermatomyositis is a rare autoimmune disease characterized by noninfectious inflammatory damage of skin and predominant muscles in the belts. It is believed to be associated with about 1 in 1000 cases of nasopharyngeal carcinoma. This association has been described for locally advanced stages II and III nasopharyngeal carcinoma. It has rarely been described in the early stages (stage I).
4p
vilazada
31-01-2024
3
2
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We evaluated the prognostic role of deficient mismatch repair (dMMR) systems in stage II and stage III colon cancer patients during different postoperative periods. We also assessed whether patients aged ≥75 could benefit from chemotherapy.
12p
vileonardodavinci
23-12-2023
6
2
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Although the prognosis of locally advanced cervical cancer has improved dramatically, survival for those with stage IIIB-IVA disease or lymph nodes metastasis remains poor. It is believed that the incorporation of intensity-modulated radiotherapy into the treatment of cervical cancer might yield an improved loco-regional control, whereas more cycles of more potent chemotherapy after the completion of concurrent chemotherapy was associated with a diminished distant metastasis.
11p
vileonardodavinci
23-12-2023
3
3
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Since the publication of MA-20 and EORTC-22922 trials, chest wall (CW)/ whole breast (WB) irradia‑ tion+comprehensive regional nodal irradiation (RNI) with internal mammary node irradiation (IMNI) has been the standard adjuvant treatment for early-stage breast cancer (BC).
8p
vileonardodavinci
23-12-2023
5
2
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Small-cell lung cancer (SCLC) accounts for 12–15% of lung cancers and has a limited prognosis, with approximately one-third of SCLC patients having a poor performance status (PS). Patients with extensive-stage (ES) SCLC and a poor PS have a poor prognosis.
6p
vileonardodavinci
23-12-2023
7
4
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This study was designed to determine the optimal combination of markers that predict recurrence in patients with T factors of T3/T4a stage II CRC by applying a novel Bayes decision rule.
10p
vileonardodavinci
23-12-2023
6
3
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The role of adjuvant radiation in pancreatic adenocarcinoma (PDAC) remains unclear. We aimed to investigate the efficacy of gemcitabine combined with stereotactic body radiation therapy (SBRT) as adjuvant therapy for resected stage II PDAC.
7p
vialfrednobel
23-12-2023
4
3
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Previous assessments of peritumoral infammatory infltrate in colorectal cancer (CRC) have focused on the role of CD8+ T lymphocytes. We sought to compare the prognostic value of CD8 with downstream indicators of active immune cell function, specifically granzyme B (GZMB) and CD68 in the tumour microenvironment.
13p
vialfrednobel
23-12-2023
4
3
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This study aimed to construct a nomogram to effectively predict the overall survival (OS) of patients with early-stage non-small-cell lung cancer (NSCLC). Methods: For the training and internal validation cohorts, a total of 26,941 patients with stage I and II NSCLC were obtained from the Surveillance, Epidemiology, and End Results (SEER) database.
13p
vialfrednobel
23-12-2023
10
3
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Accumulating evidence indicates that type II cystatin (CST) genes play a pivotal role in several tumor pathological processes, thereby affecting all stages of tumorigenesis and tumor development. However, the prognostic and predictive value of type II CST genes in GC has not yet been investigated.
17p
vialfrednobel
23-12-2023
8
3
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