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Still controversial
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Epigenetic alterations contribute greatly to the development and progression of colorectal cancer, and effect of aberrant miR-622 expression is still controversial. This study aimed to discover miR-622 regulation in CRC proliferation.
12p
vishanshan
27-06-2024
1
1
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Indocyanine green (ICG) clearance and remnant liver volume (RLV) are the two important factors in predicting post-hepatectomy liver failure (PHLF) after major hepatectomy; however, the combination of these is still controversial. This study is to find a way to combine these to select candidates for safe major hepatectomy.
8p
vikissinger
21-12-2023
1
1
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Response of locally advanced gastric cancer (LAGC) to neoadjuvant therapy (NAT) may be associated with prognosis, but which of the clinical or pathological evaluation can accurately predict a favorable prognosis is still controversial. This study aims to compare the effect of clinical and pathological response on the prognosis of patients with gastric cancer.
10p
visharma
20-10-2023
2
2
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Radical resection is still the most cost-effectiveness curative strategy for intrahepatic cholangiocarcinoma (ICC), but it remains controversial on the survival benefits of anatomic resection (AR). In this study, we sought to compare the oncologic outcomes between AR versus non-AR (NAR) as the primary treatment for early-stage ICC patients.
14p
vioracle
29-09-2023
6
2
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Dysbiosis of gut microbiota has been linked to numerous diseases, including cancer. The unique role of gut microbiota in urological tumors is gaining prominence. However, it is still controversial whether the dysbiosis of gut microbiota should be one of the etiological factors of bladder cancer (BCa), prostate cancer (PCa) or kidney cancer (KCa).
9p
vioracle
29-09-2023
4
2
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The demand for monitoring non-invasive blood pressure (NIBP) parameters in health facilities for medical examination and treatment, specifically self-monitoring at home is significantly increasing. The measurement methods are based on many different techniques. However, the accuracy and stability of the measurement results from these techniques are still controversial.
10p
viporsche
25-10-2022
11
2
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While the electroosmosis of the first kind (equilibrium) is accepted widely, the electroosmosis of the second kind (nonequilibrium) is still controversial. In this work, the theory of electroosmosis slip, of either the first kind or of the second kind at electrolyte membrane system is revisited via our direct numerical simulation.
8p
viporsche
25-10-2022
9
2
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There is still controversy regarding the clinical value and significance of lateral pelvic lymph node (LPN) dissection (LPND). The present study aimed to investigate whether the addition of LPND to total mesorectal excision (TME) confers survival benefits in rectal cancer patients with clinical lateral pelvic node metastasis (LPNM).
10p
vikolindagrabar
27-07-2022
3
1
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Local anesthesia (LA) has been reported to be the best choice for elective open inguinal hernia repair because it is cost efficient, with less post-operative pain and enables more rapid recovery. However, the role of LA in emergency inguinal hernia repair is still controversial. The aim of this study is to investigate the safety and effectiveness of LA in emergency inguinal hernia repair.
5p
viisaacnewton
25-04-2022
5
1
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The role of recombinant activated protein C (aPC) during sepsis is still controversial. It showed antiinflammatory effect and improved the microvascular perfusion in experimental models of septic shock. The present study was aimed at testing the hypothesis that recombinant aPC therapy improves the microcirculation during severe sepsis.
8p
viisaacnewton
26-04-2022
10
1
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While the impact of volatile anaesthetics to induce malignant hyperthermia (MH) is abundantly clear, the role of succinylcholine still remains controversial. To evaluate the influence of succinylcholine on porcine MH events, the authors investigated the hemodynamic and metabolic responses in MH susceptible (MHS) and non-susceptible (MHN) swine following either succinylcholine or halothane application alone or a combination of both substances.
7p
viisaacnewton
26-04-2022
6
1
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Teaching and learning ESP at universities in Vietnam has been facing many difficulties and challenges related to different issues. The concept of direct ESP instructor is still controversy with different opinions. The question is whether English teachers or specialized ones do it better? To answer this question, it is necessary to have a thorough analysis of the goals and characteristics as well as the necessary requirements for teaching ESP.
8p
hanthienngao
14-04-2022
6
1
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Embryonic stem cells are intrinsically unstable and differentiate spontaneously if they are not shielded from external stimuli. Although the nature of such instability is still controversial, growing evidence suggests that protein translation control may play a crucial role.
22p
viaristotle
29-01-2022
6
0
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Underbody blankets have recently been launched and are used by anesthesiologists for surgical patients. However, the forced-air warming effect of underbody blankets is still controversial. The aim of this study was to determine the effect of forced-air warming by an underbody blanket on body temperature in anesthetized patients.
8p
vampires36
30-12-2021
13
0
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The role of non-infective inflammatory response (IR) in the aetiology of postoperative cognitive dysfunction (POCD) is still controversial. The aim of this controlled, prospective observational study was to assess the possible relationship between the grade of IR, defined by procalcitonin (PCT) changes, and development of POCD related to cardiac surgery.
10p
vampires36
30-12-2021
7
0
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Perioperative neurocognitive disorders (PND) is a common postoperative complication including postoperative delirium (POD), postoperative cognitive decline (POCD) or delayed neurocognitive recovery. It is still controversial whether the use of intraoperative cerebral function monitoring can decrease the incidence of PND.
13p
vizhangzhidong
29-12-2021
9
0
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The incidence and risk factors of postoperative cognitive dysfunction (POCD) during robot-assisted radical cystectomy (RARC) in extreme Trendelenburg positioning and pneumoperitoneum are still controversial. The aim of this prospective observational study was to find the incidence rate as well as possible risk factors of POCD in RARC with cerebral oxygen monitoring.
9p
vizhangzhidong
29-12-2021
12
2
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Surgical resection is considered to be the primary and most effective therapy for breast cancer, postoperative pain is an issue gaining significant attention. In recent years, erector spinae plane block (ESPB) has attracted much attention in postoperative analgesia, but its effectiveness is still controversial.
12p
vidietmarhopp
28-12-2021
9
0
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Osteoporosis and cardiovascular diseases (CVDs) are 2 major public health problems. Osteoporosis and CVDs may be linked but the association between lipid profile and osteoporosis is still controversial. The purpose of this study was to examine the associations of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) with osteoporosis.
8p
vimackenziebezos
30-11-2021
11
2
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Treatment of medial clavicle fractures is still controversially discussed in the community of upper extremity surgeons. An increasing number of symptomatic non-unions following conservative treatment of displaced fractures led to the development of various surgical approaches.
7p
vimackenziebezos
30-11-2021
4
1
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