Synthesis of imidazo
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![Synthesis and anti-tuberculosis studies of 10-phenyl sulfonyl-2-alkyl/aryl- 4, 10 dihydrobenzo [4, 5] imidazo [1, 2-a] pyrimidin-4-one derivatives](https://tailieu.vn/image/document/thumbnail/2020/20200525/tocectocec/135x160/3621590394727.jpg "Synthesis and anti-tuberculosis studies of 10-phenyl sulfonyl-2-alkyl/aryl- 4, 10 dihydrobenzo [4, 5] imidazo [1, 2-a] pyrimidin-4-one derivatives")
A series of novel 10-phenylsulfonyl-2-substituted-4,10 dihydrobenzo[4,5]imidazo[1,2- a]pyrimidin-4-one derivatives obtained from N-sulfonation of 2-substituted-pyrimido[1,2- a]benzimidazol-4(10H)-ones and screened for for their in vitro anti-tuberculosis activities against Mycobacterium tuberculosis H37Rv by Microplate Alamar Blue Assay (MABA) method.
8p 
tocectocec
25-05-2020
14
1
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![Synthesis of imidazo[1,2-a]-pyridine derivatives](https://tailieu.vn/image/document/thumbnail/2015/20150924/uocvong04/135x160/6871443063840.jpg "Synthesis of imidazo[1,2-a]-pyridine derivatives")
The synthesis of imidazo[1,2-a]-pyridine derivatives was carried out by subsequential reactions: condensation, substitution and reduction, using the commercially available 2- aminopyridine as starting material.
4p uocvong04
24-09-2015
52
2
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Pharmacological activation or overexpression of glucokinase in hepatocytes stimulates glucose phosphorylation, glycolysis and glycogen synthesis. We used an inhibitor of glucose 6-phosphate (Glc6P) hydrolysis, namely the chlorogenic derivative, 1-[2-(4-chloro-phenyl)-cyclopropylmethoxy]-3, 4-di-hydroxy-5-(3-imidazo[4,5-b]pyridin-1-yl-3-phenyl-acryloyloxy)-cyclohexane-
11p dell39
27-03-2013
51
4
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