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Systemic chemotherapy
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For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before surgery, was commonly recommended as the standard treatment.
10p
vishanshan
27-06-2024
1
1
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Polymeric micelle systems for drug delivery, monitor and chemotherapy have gained significant attention, and reductive polymeric micelle systems have become particularly attractive due to their controlled release behavior without additional assistance.
9p
vishanshan
27-06-2024
1
1
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The objective of our study was to determine the proportion of patients advancing to third line chemotherapy, to outline the various third-line chemotherapy regimens used in routine practice and to evaluate their respective efficacy.
9p
vikoch
27-06-2024
1
1
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Systemic inflammatory factors can predict the survival prognosis of gastric cancer (GC) patients after neoadjuvant chemotherapy (NACT). However, whether longitudinal changes in systemic inflammatory factors are associated with short - and long-term outcomes has not been reported.
13p
vikoch
27-06-2024
2
1
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Epithelioid sarcoma is a rare soft tissue sarcoma characterized by SMARCB1/INI1 deficiency. Much attention has been paid to the selective EZH2 inhibitor tazemetostat, where other systemic treatments are generally ignored. To explore alternative treatment options, we studied the effects of irinotecan-based chemotherapy in a series of epithelioid sarcoma patients.
11p
vikoch
27-06-2024
1
1
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The current standard of care in the neoadjuvant setting for high-risk HER2-positive (HER2+) breast cancer is to combine systemic chemotherapy with dual HER2 blockade, trastuzumab and pertuzumab. Targeted therapies have significantly improved outcomes for patients with HER2-positive breast cancer.
8p
vikoch
27-06-2024
1
1
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Part 2 book "Goodman and gilmans the pharmacological basis of therapeutics" includes content: Hormones and hormone antagonists, gastrointestinal pharmacology, chemotherapy of infectious diseases, pharmacotherapy of neoplastic disease, special systems pharmacology.
649p
zizaybay1101
30-04-2024
4
2
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Part 2 book "Veterinary microbiology" includes content: Agents of subcutaneous mycoses; agents of systemic mycoses; parvoviridae; circoviridae; asfarviridae and iridoviridae; papillomaviridae and polyomaviridae; adenoviridae; herpesviridae; poxviridae; picornaviridae; caliciviridae; togaviridae and flaviviridae; orthomyxoviridae; bunyavirales; paramyxoviridae, pneumoviridae, filoviridae, and bornaviridae; rhabdoviridae; coronaviridae and tobanivi,... and other contents.
453p
muasambanhan10
03-04-2024
8
1
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Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its receptor interaction, thus obstructing the formation of new blood vessels.
14p
vibransone
28-03-2024
4
2
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The HCMC Oncology Hospital is a leading hospital in South Vietnam for diagnosing and treating cancer diseases. Therefore, this article aims to identify malnutrition status and related factors in gastric cancer patients undergoing chemotherapy treatment at HCMC Oncology Hospital in 2022. We also provided information or counseling in the high-risk groups.
11p
vilarry
12-03-2024
2
2
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Part 3 book "Small animal internal medicine" includes content: Lesion localization and the neurologic examination; diagnostic tests for nervous system and neuromuscular disorders; intracranial disorders; loss of vision and pupillary abnormalities; seizures and other paroxysmal events; head tilt; encephalitis, myelitis, and meningitis; disorders of the spinal cord; disorders of peripheral nerves and the neuromuscular junction;... and other contents.
542p
muasambanhan05
22-01-2024
3
2
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We evaluated the prognostic role of deficient mismatch repair (dMMR) systems in stage II and stage III colon cancer patients during different postoperative periods. We also assessed whether patients aged ≥75 could benefit from chemotherapy.
12p
vileonardodavinci
23-12-2023
6
2
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The modified systemic inflammation score (mSIS) system, which is constructed based on the neutrophil to lymphocyte ratio (NLR) and albumin (Alb), has not been applied to evaluate the prognosis of malignant breast cancer patients who underwent neoadjuvant chemotherapy (NAC). The present study aimed to explore the relationship between the mSIS and overall survival (OS), disease-free survival (DFS) and pathological complete response (pCR).
15p
vileonardodavinci
23-12-2023
8
3
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Chemoradiotherapy with concurrent durvalumab for the palliative treatment of oligometastatic oesophageal and gastrooesophageal carcinoma with dysphagia: A single arm phase II clinical trial (PALEO, sponsored by the Australasian Gastro-Intestinal Trials Group)
10p
vileonardodavinci
23-12-2023
3
2
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The purpose of this study was to investigate the significance of preoperative C-reactive proteinto-albumin ratio (CAR), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting overall survival (OS) of osteosarcoma, to establish a nomogram of an individualized prognostic prediction model for osteosarcoma.
9p
vileonardodavinci
23-12-2023
4
2
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It has been reported that inflammatory and nutritional markers are related to prognosis in numerous malignancies. The present study analyzed the significance of these markers’ alterations during neoadjuvant chemotherapy in the long-term outcomes in patients with advanced gastric cancer.
11p
vileonardodavinci
23-12-2023
6
2
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To compare recurrence and survival in patients with stage III endometrial cancer after radical surgery, followed by either adjuvant chemoradiotherapy (ACR) or adjuvant chemotherapy (AC).
12p
vileonardodavinci
23-12-2023
3
2
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Methotrexate (MTX) is a chemotherapy and immunosuppressive agent widely used to treat cancer, autoimmune diseases in children and adult patients, and ectopic pregnancy. However, MTX is highly toxic to the liver, kidney, and nervous system. This study aimed to quantify the concentration of MTX in human plasma using high-performance liquid chromatography (HPLC).
6p
vikissinger
21-12-2023
1
1
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Osteosarcoma (OS) mainly happens in children and youths. Surgery, radiotherapy and chemotherapy are the common therapies for osteosarcoma treatment but all their anti-tumor effects are limited.
12p
vileonardodavinci
23-12-2023
5
4
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Primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system (PCNSL) is a rare disorder with an increasing incidence over the past decades. High-level evidence has been reported for the MATRix regimen (high-dose methotrexate (HD-MTX), high-dose AraC (HD-AraC), thiotepa and rituximab) followed by high-dose chemotherapy and autologous stem cell transplantation (HCT-ASCT) supporting this approach to be considered a standard therapy in newly diagnosed PCNSL patients≤70 years.
9p
vialfrednobel
23-12-2023
6
3
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