Target bacterial infections
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Measuring host gene expression is a promising diagnostic strategy to discriminate bacterial and viral infections. Multiple signatures of varying size, complexity, and target populations have been described. However, there is little information to indicate how the performance of various published signatures compare to one another.
14p viellison 28-03-2024 5 2 Download
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Part 1 book How to overcome the antibiotic crisis - Facts, challenges, technologies and future perspectives" includes content: tackling threats and future problems of multidrug resistant bacteria, emergence and spread of antimicrobial resistance - recent insights from bacterial population genomics, diagnostics and resistance profiling of bacterial pathogens, anti virulence strategies to target bacterial infections..... and other contents.
211p oursky06 17-10-2023 5 2 Download
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It has been demonstrated that swine waste is an important reservoir for resistant genes. Moreover, the bacteria carrying resistant genes and originating from swine feces and wastewater could spread to the external environment. Fluoroquinolones (FQs) are widely used in livestock and poultry for the treatment of bacterial infections.
9p vigandhi 23-02-2022 19 1 Download
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Bacterial invasive infection and host immune response is fundamental to the understanding of pathogen pathogenesis and the discovery of effective therapeutic drugs. However, there are very few experimental studies on the signaling cross-talks between bacteria and human host to date.
21p vibeauty 23-10-2021 8 1 Download
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In 2017, World Health Organization (WHO) published a catalogue of 12 families of antibiotic-resistant “priority pathogens” that are posing the greatest threats to human health. Six of these dreaded pathogens are known to infect the human gastrointestinal system.
16p vijeeni2711 24-07-2021 9 0 Download
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The type III secretion system (T3SS) is a complex macromolecular machin-ery employed by a number of Gram-negative species to initiate infection. Toxins secreted through the system are synthesized in the bacterial cyto-plasm and utilize the T3SS to pass through both bacterial membranes and the periplasm, thus being introduced directly into the eukaryotic cytoplasm.
13p mobifone23 07-01-2013 48 3 Download
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Vancomycin Clinically important resistance to vancomycin was first described among enterococci in France in 1988. Vancomycin-resistant enterococci (VRE) have subsequently become disseminated worldwide. The genes encoding resistance are carried on plasmids that can transfer themselves from cell to cell and on transposons that can jump from plasmids to chromosomes. Resistance is mediated by enzymes that substitute D-lactate for D-alanine on the peptidoglycan stem peptide so that there is no longer an appropriate target for vancomycin binding.
5p colgate_colgate 21-12-2010 64 2 Download