Target reliability
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Breast cancer remains a significant health challenge worldwide, necessitating the identification of reliable biomarkers for early detection, accurate prognosis, and targeted therapy.
13p vikoch 27-06-2024 1 1 Download
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TCP-targeted low-rate distributed denial-of-service (LDDoS) attacks pose a serious challenge to the reliability and security of the Internet. Among various proposed solutions, we are particularly interested in the Congestion Participation Rate (CPR) metric and the CPR-based approach.
17p viambani 18-06-2024 2 1 Download
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To provide a report on year 1 results of a national study investigating nursing home information technology (IT) adoption, called IT sophistication. Methods: A reliable and valid survey was used to measure IT sophistication. The target goal was 10% from each state in the United States, 1570 nursing homes. A random sample of homes from each state was recruited from Nursing Home Compare.
7p visteverogers 24-06-2023 3 2 Download
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This study comes up with building integration of evaluation teaching scale at higher education institutions in Vietnam, according to the example of Blended Learning, in response to the process of teaching. This scale with criterias about Blended learning set the targets to evaluate the effectiveness and the ability of far-reaching of this teaching method at higher education institutions in Vietnam. This scale is tested and checked for reliability to be applied in the next research.
12p viantman 07-04-2023 7 2 Download
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Bangladesh lies in the global thalassemia belt, which has a defined mutational hot-spot in the betaglobin gene. The high carrier frequencies of beta-thalassemia trait and hemoglobin E-trait in Bangladesh necessitate a reliable DNA-based carrier screening approach that could supplement the use of hematological and electrophoretic indices to overcome the barriers of carrier screening.
12p vinarcissa 21-03-2023 2 1 Download
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In the last decade, the consumption trend of organic food has increased dramatically worldwide. However, the lack of reliable chemical markers to discriminate between organic and conventional products makes this market susceptible to food fraud in products labeled as “organic”.
11p viginny 23-12-2022 7 3 Download
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We present the software Condition-specific Regulatory Units Prediction (CRUP) to infer from epigenetic marks a list of regulatory units consisting of dynamically changing enhancers with their target genes. The workflow consists of a novel pre-trained enhancer predictor that can be reliably applied across cell types and species, solely based on histone modification ChIP-seq data.
23p vielonmusk 30-01-2022 12 0 Download
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In recent years the Illumina HumanMethylation450 (HM450) BeadChip has provided a user-friendly platform to profile DNA methylation in human samples. However, HM450 lacked coverage of distal regulatory elements. Illumina have now released the MethylationEPIC (EPIC) BeadChip, with new content specifically designed to target these regions.
17p viaristotle 29-01-2022 5 0 Download
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The song repertoire across avian species varies considerably in size, and reliable measurement is important in defining its significance as a target in sexual selection. In this study, the song structure and song repertoire size of the Daurian Redstart (Phoenicurus auroreus) in South Korea were investigated. The songs had major syllable variation rather than song type variation. The average song repertoire size from 20 males was 39.9 ± 5.8 (range: 28–50), based on a syllable type that was appropriate for this species.
9p dolomite36 30-12-2021 4 0 Download
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Enhancers are distal cis-regulatory elements that control gene expression. Despite an increasing appreciation of the importance of enhancers in cellular function and disease, our knowledge of enhancer-regulated transcription is very limited.
18p vitzuyu2711 29-09-2021 11 1 Download
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Archived formalin fixed paraffin embedded (FFPE) samples are valuable clinical resources to examine clinically relevant morphology features and also to study genetic changes. However, DNA quality and quantity of FFPE samples are often sub-optimal, and resulting NGS-based genetics variant detections are prone to false positives.
10p visilicon2711 20-08-2021 8 1 Download
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In quantitative real-time polymerase chain reaction (qRT-PCR) experiments, accurate and reliable target gene expression results are dependent on optimal amplification of house-keeping genes (HKGs). RNA-seq technology offers a novel approach to detect new HKGs with improved stability.
16p vijeeni2711 24-07-2021 5 0 Download
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This paper is devoted to the variant of synthesis of a radar recognition algorithm with the ability to meet reliability of decisions. The algorithm is based on the theory of sequential analysis in combination with flexible change in the level of the classification detail when the observation time cannot be increased. Compared with one-step algorithms, the proposed algorithm allows guaranteeing “the posteriori probability of decisions is not smaller than the set value”. The proposed algorithm can be used in radar target recognition systems.
9p cothumenhmong11 05-05-2021 13 1 Download
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Scoliosis is a spine abnormal deviation, which is an idiopathic disorder among children and adolescents. As a matter of the fact, distribution of loads on the patient’s spine and load-carrying capacity of the vertebral column are both random variables.
12p vimariana2711 22-12-2020 8 1 Download
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Digital polymerase chain reaction (dPCR) is an increasingly popular technology for detecting and quantifying target nucleic acids. Its advertised strength is high precision absolute quantification without needing reference curves. The standard data analytic approach follows a seemingly straightforward theoretical framework but ignores sources of variation in the data generating process.
13p vikentucky2711 26-11-2020 14 1 Download
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Amplicon-based targeted resequencing is a commonly adopted solution for next-generation sequencing applications focused on specific genomic regions. The reliability of such approaches rests on the high specificity and deep coverage, although sequencing artifacts attributable to PCR-like amplification can be encountered.
12p vioklahoma2711 19-11-2020 13 2 Download
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Targeted Next Generation Sequencing (NGS) assays are cost-efficient and reliable alternatives to Sanger sequencing. For sequencing of very large set of genes, the target enrichment approach is suitable. However, for smaller genomic regions, the target amplification method is more efficient than both the target enrichment method and Sanger sequencing.
9p viflorida2711 30-10-2020 15 1 Download
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The identification of prognostic genes that can distinguish the prognostic risks of cancer patients remains a significant challenge. Previous works have proven that functional gene sets were more reliable for this task than the gene signature.
11p vicoachella2711 27-10-2020 8 0 Download
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Hodgkin Lymphoma (HL) is a type of aggressive malignancy in lymphoma that has high incidence in young adults and elderly patients. Identification of reliable diagnostic markers and efficient therapeutic targets are especially important for the diagnosis and treatment of HL.
13p vicolorado2711 23-10-2020 5 0 Download
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White rust caused by a fungus Albugo candida, is a destructive disease of many economically important species of Brassica, to control this resistance breeding is important .Marker validation is useful for testing reported markers in determining the target phenotypes in autonomous populations and dissimilar genetic backgrounds and also involves testing the reliability of marker to predict the phenotype, which defines whether or not a marker could be used in routine screening for MAS.
8p caygaocaolon7 18-09-2020 13 0 Download