The cells of our body

This book explores big questions like these, explaining the breakthroughs and discoveries that have shaped our modern-day understanding of medicine and helped us protect and promote our health. Written in plain English, The Medicine Book cuts through the jargon and is packed with pithy explanations of the most important milestones in medical history, with step-by-step diagrams and witty illustrations that untangle knotty concepts. Please refer to Ebook The Medicine Book: Big ideas simply explained - Part 1 for more details.

163p haojiubujain03 09-08-2023 5 3   Download

Here we utilized RNA sequencing (RNAseq) using HEK293 cells overexpressing isoforms 1 or 3 (Iso1, Iso3 cells), in combination with the coding non-risk or risk (*WWCC) haplotype of CCHCR1. Our aim was to study the overall role of CCHCR1 and the effects of its variants.

15p vibeauty 23-10-2021 13 1   Download

A neuroendocrine tumor (NET) can develop anywhere in the body, but is mainly found in the pancreas, gastrointestinal tract, and lungs. This report is a retrospective study of the clinicopathological features of NET patients with brain metastasis whose tissue diagnosis was made at our hospital.

8p vinaypyidaw2711 26-08-2020 13 2   Download

Phellinus gilvus (Schwein.) Pat, a species of ‘Sanghuang’, has been well-documented for various medicinal uses, but the genome information and active constituents are largely unknown. Here, we sequenced the whole-genome of P. gilvus, identified phenylpropanoids as its key anti-cancer components, and deduced their biosynthesis pathways. A 41.11-Mb genome sequence was assembled and the heatmap created with high-throughput chromosome conformation capture techniques data suggested all bins could be clearly divided into 11 pseudochromosomes. Cellular experiments showed that P.

11p covid19 14-06-2020 26 0   Download

Pesticides such as Rogor, Endosulfan, DDT, Daminozole etc. are commonly used to meet the enormous demand of fodder crops. These exert adverse effects at both biochemical and cellular level. They cause several chronic diseases like skin diseases, cancer, liver problems, neural and hormonal diseases. Gross symptoms of damages are seen in very late stages. Thus, present investigation was undertaken to evaluate ultrastructural changes under Scanning Electron Microscope (SEM).

4p nguathienthan1 27-11-2019 22 1   Download

We introduce an inclusion-field technique for fast detection of collisions between a highly deformable object and another object with limited deformations. We mainly target the cloth simulation application where cloth (highly deformable) collides with deforming skin of a moving human model (has limited deformation as skin stretches and compacts within finite spacial and temporal limits specified by the bending angle and speed). Our technique intermixes concepts from space voxelization and distance fields to make use of the limited deformation nature of human skin.

8p kethamoi1 17-11-2019 17 0   Download

Our body is endowed with several endogenous anti-microbial compounds such as interferon, cytokines, free radicals, etc. However, little attention has been paid to the possibility that lipids could function as antimicrobial compounds. In this short review, the antimicrobial actions of various polyunsaturated fatty acids (PUFAs, mainly free acids) and their putative mechanisms of action are described.

10p trinhthamhodang1 14-11-2019 12 1   Download

The dementia familial encephalopathy with neuroserpin inclusion bodies (FENIB) is caused by point mutations in the neuroserpin gene.We have shown a correlation between the predicted effect of the mutation and the number of intracerebral inclusions, and an inverse relationshipwith the age of onset of disease. Our previous work has shown that the intraneuronal inclusions in FENIB result from the sequential interactionbetween the reactive centre loopofone neuroserpin molecule withb-sheet A of the next. ...

0p awards 05-04-2013 27 1   Download

We normally think of the eye as an organ for vision, but due to the discovery of additional nerve connections from recently-detected novel photoreceptor cells in the eye to the brain, it is now understood how light also mediates and controls a large number of biochemical processes in the human body. The most important findings are related to the control of the biological clock and to the regulation of some important hormones through regular light-dark rhythms. This in turn means that lighting has a large influence on health, well-being and alertness.

273p namde01 07-03-2013 99 15   Download

Although the part of our bodies most affected by air pollution is the respiratory system, the circulatory system can also be affected. Exposure to unhealthy levels of air pollutants can result in low oxygen levels in red blood cells, abnormal heart rhythms, and increased risks of blood clots and narrowing of blood vessels. These effects can lead to worsening of heart diseases such as heart failure and increased risks of heart attacks or strokes. The Pollutants Chart: Sources and Effects of Air Pollutants summarize the sources and health effects of criteria air pollutants.

46p saimatkhauroi 01-02-2013 74 4   Download

From microorganisms to whales, from single cells to complex organisms, from plants to animals to fungi, from body plans to behavior, the diversity of life is amazing. Living organisms have a profound impact on our physical world of ocean, landscape, and climate; around us is a multitude of diverse ecosystems that provide a livable environment and many valuable resources. The study of life—biology—is a multifaceted endeavor that uses observation, exploration, and experiments to gather information and test hypotheses about topics ranging from climate change to stem cells.

209p mnemosyne75 02-02-2013 45 5   Download

It is hoped that this little work may assist in the search along the dark path upon which many a poet and—in later times—many an investigator has set his feet. It would not be worthy of us, whom science and technical ability has raised to so high an intellectual position as explorers of Nature in every field—should we neglect anything however trivial, deeming it as beneath our notice. We know so much about all that lies around us: the manner in which the cells build our bodies; how the juices circulate within the plant. We feel Nature to be...

147p nguyenhuucanh1212 23-01-2013 44 4   Download

This book provides information on alternative and complementary therapies that can expand the healing spectrum for individuals with spinal cord injury (SCI). It discusses healing perspectives and paradigms that have not been a part of traditional modern medicine but that, nevertheless, comprised a key component of healing armamentaria throughout much of mankind’s history.

226p cronus75 18-01-2013 63 10   Download

At best, it is a source of strength, beauty, and wonder. We can compare the healthy body to a well-designed machine whose parts work smoothly together. We can also compare it to a symphony orchestra in which each instrument has a different part to play. When all of the musicians play together, they produce beautiful music. From a purely physical standpoint, our bodies are made mainly of water.We are also made of many minerals, including calcium, phosphorous, potassium, sulfur, sodium, chlorine, magnesium, and iron.

119p cronus75 14-01-2013 41 5   Download

The vitamins are a chemically disparate group of compounds whose only common feature is that they are dietary essentials that are required in small amounts for the normal functioning of the body and maintenance of metabolic integrity.Metabolically, they have diverse functions, such as coenzymes, hormones, antioxidants, mediators of cell signaling, and regulators of cell and tissue growth and differentiation.

511p cronus75 14-01-2013 62 15   Download

Less common uterine cancers that do not come from glandular tissue of the endometrium are called uterine sarcomas. These types of cancer are not covered here because their treatment and outlook for survival are different from the most common cancers of the endometrium. If you would like to know more about this type of cancer please see our document called Uterine Sarcoma. Cervical cancers Cancers that start in the cervix and then spread to the body of the uterus are different from cancers that start in the body of the uterus.

6p taisaokhongthedung 09-01-2013 44 2   Download

In most cases the cancer cells form a tumor. Some cancers, like leukemia, rarely form tumors. Instead, these cancer cells involve the blood and blood-forming organs and circulate through other tissues where they grow. Cancer cells often travel to other parts of the body, where they begin to grow and form new tumors that replace normal tissue. This process is called metastasis. It happens when the cancer cells get into the bloodstream or lymph vessels of our body.

74p khongmuonnghe 07-01-2013 41 2   Download

Cell culture is practiced extensively throughout the world today. The techniques required to allow cells to grow and be maintained outside the body have been developed throughout the 20th century. In the 50 years since the publication of the first human cancer cell line, HeLa (1), thousands of cell lines representing most of the spectrum of human cancer have been derived. These have provided tools to study in depth the biochemistry and molecular biology associated with individual cancer types and have helped enormously in our understanding of normal as well as cancer cell physiology.

335p tom_123 15-11-2012 86 16   Download

Insoluble or low-solubility nanoparticles in biological fluid are the greatest cause for concern. Because of their tiny size, several studies have shown behaviour unique to NP. Some of them can pass through our various defence mechanisms and be transported through the body in insoluble form. Thus, some NP can end up in the bloodstream after passing through all the respiratory or gastrointestinal membranes. They are then distributed to various organs and accumulate at specific sites.

0p quynho77 10-11-2012 41 1   Download

A need for a book on immunology which primarily focuses on the needs of medical and clinical research students was recognized. This book is relatively short and contains topics considered relevant to the understanding of human immune system and its role in health and diseases. Immunology is the study of our protection from foreign macromolecules or invading organisms and our responses to them. These invaders include viruses, bacteria, protozoa or even larger parasites.

484p wqwqwqwqwq 23-07-2012 85 12   Download