The earliest time
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In this study, we investigated whether osteoporosis-like phenotype could be induced in the transgenic larvae when heat-shock was applied at earlier time points, namely when larvae were at 1,2,3,4,5, or 6 dpf. The obtained results show that heat-shocks from the time point of 3 dpf onwards resulted in osteoporosis-like phenotype, while heat-shock at 1 or 2 dpf did not affect mineralized bone matrix in 11 dpf larvae.
7p guitaracoustic02 08-12-2021 8 1 Download