The first generation

Both first and second-generation EGFR-TKIs are recommended in advanced NSCLC with common EGFR mutations. However, there are few data on the difference in efficacy of EGFR-TKIs based on the type of EGFR mutation and agents.

10p vishanshan 27-06-2024 1 1   Download

In this study, human induced pluripotent stem cells (hiPSCs) were successfully differentiated into cardiomyocytes and subsequently used to generate spheroids via the hanging drop method. We comprehensively characterized the formation, fusion, and beating capability of the generated spheroids.

11p viambani 18-06-2024 1 0   Download

Part 1 book "Power system operations and electricity markets" includes content: The evolution of the electric power industry, restructuring and the transition to more competitive power markets, the first major challenges to the system - The California restructuring experience, power marketers in a restructured power industry, the role of distributed energy resources in a restructured power industry, independent power generation, understanding both technical and business factors, the North American bulk electric system.

79p dianmotminh03 17-06-2024 2 0   Download

We aimed to identify the T790M mutation rate and clinical factors predicting the occurrence of acquired T790M mutations in advanced non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations after first- and secondgeneration tyrosine kinase inhibitor (TKI) treatment.

9p vicarlos 16-05-2024 1 0   Download

This study extracts images from Taekwondo videos and generates skeleton data from frames using the Fast Forward Moving Picture Experts Group (FFMPEG) technique using MoveNet. After that, we use deep learning architectures such as Long Short-Term Memory Networks, Convolutional Long Short-Term Memory, and Longterm Recurrent Convolutional Networks to perform the poses classification tasks in Taegeuk in Jang lessons. This work presents two approaches. The first approach uses a sequence skeleton extracted from the image by Movenet.

26p dianmotminh02 03-05-2024 3 1   Download

Ebook "Photocatalytic semiconductors: Synthesis, characterization, and environmental applications" provide an overview of the semiconductor materials from first- to third-generation photocatalysts and their applications in wastewater treatment and water disinfection. The book further presents economic and toxicological aspects in the production and application of photocatalytic materials.

298p tudohanhtau1006 29-03-2024 2 1   Download

Several polygenic risk scores (PRS) have been developed for cardiovascular risk prediction, but the additive value of including PRS together with conventional risk factors for risk prediction is questionable. This study assesses the clinical utility of including four PRS generated from 194, 46K, 1.5M, and 6M SNPs, along with conventional risk factors, to predict risk of ischemic heart disease (IHD), myocardial infarction (MI), and first MI event on or before age 50 (early MI).

16p vibransone 28-03-2024 3 2   Download

To demonstrate the causative role of gut microbiome in human health and diseases, we first need to identify, via next-generation sequencing, potentially important functional members associated with specific health outcomes and disease phenotypes.

12p vibransone 28-03-2024 2 2   Download

The low level of financial satisfaction of Generation Z will make them stressed about their future. This study aims to improve the financial satisfaction of Generation Z with Multiple Linear Regression and Regression Models with interaction supply chain strategies. Samples were used as many as 246 respondents from 263 questionnaires distributed in Pekanbaru City using convenience and purposive sampling methods, namely the Generation Z age criteria.

10p longtimenosee06 27-03-2024 8 2   Download

Ebook "Plant physiology" examines three ways plants respond to their changing environment. The first example can be found in all plants. Despite the extreme changes in weather, plants have to stay where they are and respond to whatever nature produces. Plants have the capacity to respond quickly and yet they can evolve in a single generation. The second example addresses how an individual leaf has to respond rapidly and repeatedly to maintain the proper balance of carbon dioxide (CO2) and water so that it can photosynthesize but not dry out.

57p manmanthanhla0201 26-02-2024 6 1   Download

Ebook "Species diversity and community structure: Novel patterns and processes in plants, insects, and fungi" introduces recent progress in the study of species diversity and community structures in terrestrial organisms conducted by three groups at Kyoto University. First, it explains species diversity and the functioning of fungi in Asian regions as outlined by metagenomic approaches using next-generation sequencing technology. The advances in high-throughput sequencing technologies accelerate the speed of species inventorying, especially for microorganisms.

70p manmanthanhla0201 26-02-2024 2 1   Download

Ebook "Photons in natural and life sciences: An interdisciplinary approach (Springer series in optical sciences, Volume 157)" describes first the principle photon generation processes from nuclear reactions, electron motion and from discrete quantum transitions. It then focuses on the use of photons in various selected fields of modern natural and life sciences. It bridges disciplines such as physics, chemistry, earth- and materials science, proteomics, information technology, photoelectrochemistry, photosynthesis and spintronics.

301p manmanthanhla0201 26-02-2024 6 1   Download

Ebook "Synthesis of heterocycles via cycloadditions I" present five selected contributions by well-known authors, each an authority in his field. The first chapter deals with construction of isoxazolines (dihydroisoxazoles) via 1,3-dipolar cycloadditions of nitronates or of nitrile oxides generated from nitroalkanes. This includes inter- as well as intramolecular processes.

239p manmanthanhla0201 27-02-2024 2 1   Download

Part 1 book "Advanced engineering thermodynamics" includes content: The first law, the second law, entropy generation, or exergy destruction, single phase systems, power generation, exergy analysis, chemically reactive systems, multiphase systems.

429p muasambanhan06 01-02-2024 11 1   Download

Ebook "Cognitive development in Chimpanzees" on cognitive development in chimpanzees is the first of its kind to focus on infants reared by their own mothers within a natural setting, illustrating various aspects of chimpanzee cognition and the developmental changes accompanying them. The subjects are chimpanzees of three generations inhabiting an enriched environment, as well as a wild community in West Africa.

539p tachieuhoa 28-01-2024 4 2   Download

Ebook "Rangeland stewardship in Central Asia: Balancing improved livelihoods, biodiversity conservation and land protection" is rich with new data presented in 68 easy to understand charts/graphs (many in color) and 50 Tables. Information was generated for this book by experts working in-country.

479p tachieuhoa 28-01-2024 4 2   Download

Part 1 book "Genomics in aquaculture" includes content: The new era of genome sequencing using highthroughput sequencing technology - Generation of the first version of the Atlantic cod genome; the rainbow trout genome, an important landmark for aquaculture and genome evolution; an improved version of the Atlantic cod genome and advancements in functional genomics - implications for the future of cod farming.... and other contents.

135p muasambanhan04 11-01-2024 8 1   Download

This specification covers the determination of heat stability of steam turbine shafts and rotor forgings to ensure stability at operating temperature. This specification is not ordinarily applicable to generator rotor forgings.

3p hth_hn_vn 10-12-2023 7 3   Download

In this paper, the control design for the grid-connected converter used as a part of the wind turbine generator is discussed. First, the three-phase T-type multilevel converter, which exhibits several advantages such as low total harmonic distortion, reduced voltage stress, and switching loss, is employed for the power stage. Second, finite control set model predictive control (FCS-MPC) is adopted to achieve a multi-objective optimization solution for the inner grid-connected current control loop.

8p vibranson 30-11-2023 5 5   Download

Ebook "Social media marketing in tourism and hospitality" describes ongoing developments in social media within the tourism and hospitality sector, highlighting impacts on both the demand and the supply side. It offers a combination of theory and practice, with discussion of real-life business experiences. The book is divided into three parts, the first of which provides an overview of recent trends in social media and user-generated content, clarifies concepts that are often used in an overlapping way and examines the “digitization of word of mouth” via online networks.

178p dangsovu 20-10-2023 8 6   Download