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The increase in in vitro
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The need for intelligent and effective treatment of diseases and the increase in drug design costs have raised drug repurposing as one of the effective strategies in biomedicine. There are various computational methods for drug repurposing, one of which is using transcription signatures, especially single-cell RNA sequencing (scRNAseq) data, which show us a clear and comprehensive view of the inside of the cell to compare the state of disease and health.
11p
vishanshan
27-06-2024
1
1
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Heterotopic pregnancies are increasing in incidence with the advent of rising prevalence of in vitro fertilization and embryo transfer (IVF-ET) globally. Although rare, this condition is a serious potentially life-threatening gynaecological complication.
5p
vitiki
30-01-2024
6
2
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The incidence of primary liver tumors, hepatocellular carcinoma (HCC), intrahepatic cholangiocellular carcinoma (ICC), and combined HCC/ICC (cHCC/CC) is increasing. For ICC, targeted therapy exists only for a small subpopulation of patients, while for HCC, Sorafenib and Lenvatinib are in use.
11p
vileonardodavinci
23-12-2023
5
2
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With the changing of lifestyles globally, the demand for ready-to-eat (RTE) foods has increased. This study investigated the effects of potato variety and product form on the total phenolic content, in-vitro digestibility and predicted glycaemic index of chips and crisps.
9p
viisac
23-09-2023
2
1
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The prevalence of Gram-positive Staphylococcus aureus in infectious diseases is increasing in Vietnam for recent years. Therefore, novel class of antibiotic or active compounds is indispensable to treat this common worldwide pathogen. In the present study, we investigated the antibacterial activities of Cleistocalyx operculatus (Roxb.) Merr. et Perry leaves collected in Quang Nam.
5p
viwarmachine
01-07-2023
1
1
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Gerbera jamesonii is a popular flower. Currently, the demand for growing gerbera jamesonii pots to decorate offices, campuses and Tet holidays is increasing. Red gerbera jamesonii bolus with black stamens with large flower diameter is very popular in the market
8p
vimalfoy
08-02-2023
5
1
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The selection of a wound dressing is crucial for successful wound management. Conventional dressings are preferable for the treatment of simple wounds. However, a bioactive wound dressing that supports wound management and accelerates the healing process is required when it comes to treating non-self-healing wounds. 2-deoxy-D-ribose (2dDR) is a small deoxy sugar that naturally occurs in human body.
16p
lyhuyenthu
31-01-2023
7
2
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In the micropropagation of difficult-to-root plants, the low rates of rooting cause high economic losses. The local apple (Malus domestica Borkh.) cultivar #67, which is highly resistant to fire blight disease, has been shown to have low rooting success. Nanoparticles loaded with auxins could increase the rooting success with their physicochemical properties.
12p
lyhuyenthu
31-01-2023
6
2
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Chitooligosaccharides (COS) have garnered great attention in the field of human healthcare. The prebiotic activities and antiglycation of COS were investigated using a combination of in vitro and in vivo studies. COS supplementation dramatically increased the levels of acetic acid, while reducing the concentrations of propionic and butyric acids.
9p
viginny
30-12-2022
11
2
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Successful treatment of skin infections requires eradication of biofilms found in up to 90 % of all chronic wounds, causing delayed healing and increased morbidity. We hypothesized that chitosan hydrogel boosts the activity of liposomally-associated membrane active antimicrobials (MAA) and could potentially improve bacterial and biofilm eradication.
10p
viginny
30-12-2022
3
2
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Mild hypothermia (34–35 °C) increases perioperative blood loss. Our previous studies showed that desmopressin could have in vitro beneficial effects on hypothermia-induced primary haemostasis impairment. In this study, we investigate the in vitro effects of desmopressin on hypothermia-induced primary haemostasis impairment under the influence of aspirin in healthy volunteers.
7p
viisaacnewton
25-04-2022
5
1
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Early goal directed therapy improves survival in patients with septic shock. Central venous pressure (CVP) monitoring is essential to guide adequate resuscitation. Use of peripherally inserted central catheters (PICC) is increasing, but little data exists comparing a PICC to a conventional CVP catheter. We studied the accuracy of a novel PICC to transmit static and dynamic pressures in vitro.
7p
viisaacnewton
26-04-2022
18
2
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The warming climate is causing livestock to experience heat stress at an increasing frequency. Holstein cows are particularly susceptible to heat stress because of their high metabolic rate. Heat stress negatively affects immune function, particularly with respect to the cell-mediated immune response, which leads to increased susceptibility to disease.
11p
vidarwin
23-02-2022
14
1
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The calcium sensitizer levosimendan is increasingly used to improve hemodynamics in patients with acutely decompensated heart failure. By binding to cardiac troponin C the conformation of the calcium-troponin C complex is stabilized, which leads to acceleration of actin-myosin crossbrigde formation and increased force generating capacity of muscle fibers.
5p
vampires36
30-12-2021
15
0
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The increase in endotracheal tube cuff pressure due to nitrous oxide diffusion is a well-known risk during general anesthesia using nitrous oxide. We hypothesized that lubricating endotracheal tube cuffs with K-Y™ Jelly might inhibit the increase in cuff pressure that occurs during exposure to nitrous oxide.
7p
vampires36
30-12-2021
8
0
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The crude protein increased from 3.60% to 11.80% when S. cerevisiae was used as biological additive material after incubation of 7 days at 28 C. Cellulose, hemicellulose and lignin showed gradual decrease with increasing incubation time of the fermentation process, however, in vitro disappearance increased.
5p
schindler
30-12-2021
10
1
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We previously demonstrated that lubrication of an endotracheal tube (ETT) cuff with K-Y™ jelly strongly and significantly inhibited the increase in cuff pressure during nitrous oxide (N2O) exposure in vitro.
8p
vizhangzhidong
29-12-2021
13
0
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The highest significant values of total soluble sugars and their fractions were noted in explant stage. Embryogenic callus stage induced a significant increase in total soluble sugars, free amino acids, phenols and indoles concentrations as compared to callus and mature somatic embryo.
8p
schindler
30-12-2021
13
0
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Hundred percent of microtuber below 250 mg induced in 3% sucrose concentration and from then the microtuber grade induction decreased with the increase of sucrose concentration. >500 mg grade microtuber produced by Granola (47.95%) with 10% sucrose while Diamant produced 50.15% above 500 mg grade microtuber with 14% sucrose.
7p
schindler
30-12-2021
6
0
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In this research, we have compared the developing embryos in vitro capacity of oocytes collected from slaughtered cows and ones collected by Ovum Pick Up (OPU) from living cows. As the result showed that, by OPU technology, we have collected many high quality oocytes, that increased the developing capacity of the oocytes grown in vitro. Therefore, that increased the percentage fertilization and the developing capacity of the embryos grown in vitro.
5p
thienlangso
15-12-2021
17
0
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