The pulse function
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Glycoprotein (GP) V is noncovalently linked to GPIba, GPIbband GPIX within the platelet GPIb–V–IX complex, a receptor for von Willebrand factor and thrombin. Two functions have been ascribed to GPV, namely, the modula-tionof thrombin- andcollagen-dependent platelet responses. The biosynthesis of this molecule was investigated in pulse– chase metabolic labelling experiments performed in CHO cell lines transfected with GPV, alone or in the presence of GPIb–IX.
0p 
awards
05-04-2013
32
3
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The temporal aspects of signaling are critical to the function of signals in communications, feedback regulation and control. The production and transduction of biological signals by enzymes comprises an area of central importance and rapid progress in the biomedical sciences.
12p viettel02
20-02-2013
28
2
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