Their mechanisms

Aberrant expressions of desmoglein 2 (Dsg2) and desmocollin 2(Dsc2), the two most widely distributed desmosomal cadherins, have been found to play various roles in cancer in a context-dependent manner. Their specific roles on breast cancer (BC) and the potential mechanisms remain unclear.

15p vishanshan 27-06-2024 1 1   Download

Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer mortality. Nevertheless, little is known about the underlying molecular mechanisms. This research aimed to investigate differentially expressed genes (DEGs) and explore their function in Lewis lung carcinoma (LLC)-bearing mice exposed to chronic intermittent hypoxia (CIH) by transcriptome sequencing.

10p vishanshan 27-06-2024 1 1   Download

A growing number of expression quantitative trait loci (eQTLs) have been found to be linked with tumorigenesis. In this article, we employed integrated Mendelian randomization (MR) analyses to identify novel susceptibility genes in renal cancer (RC) and reveal their potential mechanisms.

10p vikoch 27-06-2024 1 1   Download

In the field of additive manufacturing, the design and fabrication of lattice structures have garnered substantial attention, particularly for their potential in advanced material applications. This study focuses on the mechanical properties of titanium alloy Ti64 lattice structures fabricated by Laser Powder Bed Fusion.

11p visergeyne 18-06-2024 0 0   Download

This article employs qualitative research methods, encompassing analytical, synthetic, and comparative approaches, to offer insights and observations on this subject. The findings of this research endeavor culminate in a set of recommendations aimed at empowering businesses to more effectively embrace their social responsibilities, with a focus on state support as a catalytic mechanism.

14p leminhvu111 07-06-2024 0 0   Download

Studying engineering, whether it is mechanical, electrical, aeronautical, communications, civil, construction or systems engineering, relies heavily on an understanding of mathematics. In fact, it is not possible to study any engineering discipline without a sound knowledge of mathematics.

1184p zizaybay1103 29-05-2024 2 2   Download

The last decade has seen an explosion in our understanding of how bacterial pathogens trick, cajole, usurp and parasitize their various hosts. This renaissance is due to the convergence of molecular and cellular techniques with the power of microbial genetics. The purpose of this volume is to introduce recent advances in understanding selected systems chosen from both plant and animal hosts of bacterial pathogens.

347p vimeyers 29-05-2024 4 2   Download

This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes.

249p vimeyers 29-05-2024 3 2   Download

Ebook "Materials selection and design" presents topics on the basics of materials selection and design which will give a better understanding on the selection methods and then find suitable materials for the applications. This book draws the simple and straightforward quantitative methods followed by knowledge-based expert system approach with real and tangible case studies to show how undergraduate or post-graduate students or engineers can apply their knowledge on materials selection and design.

127p giangdongdinh 28-05-2024 4 2   Download

Ebook "Lymphangiogenesis in cancer metastasis" covers all aspects of this new field from the fundamental role that protein growth factors and their receptors play in lymphangiogenesis to the potential application of these advances to cancer diagnosis and treatment. Other clinical aspects explored include the mechanisms and importance of lymph node metastasis, the role of the lymphatics in lymphangioleiomyomatosis and Kaposi’s sarcoma, and approaches for imaging lymphatics in cancer.

254p dongmelo 27-05-2024 6 2   Download

Part 1 book "Foundations of geometric continuum mechanics" includes content: Introduction, prelude - Finite dimensional systems, simplices in affine spaces and their boundaries, uniform fluxes in affine spaces, from uniform fluxes to exterior algebra, smooth analysis on manifolds - A short review, interlude - Smooth distributions of defects, smooth fluxes, frames, body points, and spacetime structure, stresses, smooth electromagnetism on manifolds.

196p dianmotminh01 14-05-2024 2 0   Download

The objective of this study is to use theoretical calculations to clarify the nature of the interactions between the metal atoms and g-C3N4, thereby explaining their influence on the electronic and optical properties of the material with an emphasis on elucidating the optical absorption mechanism and the photogenerated electron-hole separation.

8p dianmotminh02 03-05-2024 5 1   Download

Additionally, factors like pH, the amount of dye, the amount of the substance under study, and the brightness of the light were examined for their impact on the reaction rate. The efficiency of the reaction in using light was calculated. Finally, a possible explanation of how the reaction works was formulated in the proposed mechanism.

11p dianmotminh02 03-05-2024 3 2   Download

Ebook "Nuclear reprogramming and stem cells" provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years. Nuclear Reprogramming and Stem Cells will serve as a valuable resource for all researchers in the field of stem cell biology, including those just setting out on their career path as well as those already established in the field.

340p ladongphongthanh1008 22-04-2024 3 2   Download

This research seeks to evaluate the degree of inclusion of the gender perspective and the promotion of education in and for equality in the historical narratives of students in Chilean Secondary Education (n = 105). The study focuses on the analysis of the discursive-narrative mechanisms employed by the students and, in particular, of their representations of gender relations.

15p viarnault 25-04-2024 4 1   Download

Ebook "The neuropilins: Role and function in health and disease" covers basic research topics such as the structure-function relationships of neuropilins and mechanisms of neuropilin-mediated signal transduction, details the most important roles of the neuropilins in developmental biology, and addresses their roles in various conditions such as cancer and various eye diseases.

236p ladongphongthanh1008 22-04-2024 8 4   Download

Ebook "TNF receptor associated factors (TRAFs)" is the only literature that is entirely devoted to TRAFs. Almost every aspect of TRAF signaling is covered, including the different TRAF family members, their distinct biological functions, the TRAF structures, their modes of receptor recognition, the signaling mechanisms, and the roles of TRAFs in normal cellular functions and in viral infection.

222p ladongphongthanh1008 22-04-2024 1 1   Download

Ebook "The long and short noncoding RNAs in cancer biology" conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance).

455p tracanhphuonghoa1007 22-04-2024 4 2   Download

Ebook "Tumor-induced immune suppression: Mechanisms and therapeutic reversal" present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance.

304p tracanhphuonghoa1007 22-04-2024 3 1   Download

Ebook "Cancer biology and the nuclear envelope: Recent advances may elucidate past paradoxes" presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer.

610p tracanhphuonghoa1007 22-04-2024 2 1   Download