Thrombotic thrombocytopenic purpura

Various hematological abnormalities including coagulation factor abnormalities, leukocytosis, acute hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura, and disseminated intravascular coagulopathy have been reported in acute pancreatitis patients. The aim of this study is to describe characteristics of coagulation disorders in children with acute pancreatitis at the Vietnam National Children’s Hospital.

8p vilarry 12-03-2024 4 1   Download

Ban xuất huyết giảm tiểu cầu huyết khối (Thrombotic thrombocytopenic purpura = TTP) là một hội chứng đặc trưng bởi tình trạng giảm tiểu cầu, thiếu máu tán huyết vi mạch kèm theo giảm hoạt tính của metalloproteinases (ADAMTS13) – men phân tách yếu tố von Willebrand. Bệnh có thể do di truyền hay mắc phải. Bài viết trình bày khảo sát các đặc điểm huyết và kết quả điều trị trên bệnh nhi tại Bệnh viện Nhi Đồng 1.

7p vibranson 06-12-2023 7 4   Download

Congenital thrombotic thrombocytopenic purpura (cTTP) is an inherited disease that is sometimes fatal in early childhood. cTTP is similar to idiopathic thrombotic thrombocytopenic purpura (iTTP); both are characterized by varying levels of thrombocytopenia, microangiopathic hemolytic anemia (MAHA), and end-organ damage secondary to occlusion of the microvasculature.

4p viintuit 26-09-2023 5 0   Download

Pernicious anemia is an autoimmune disorder that is characterized by the presence of autoantibodies to intrinsic factor and parietal cells which results in the inability to absorb vitamin B12. It is the most common manifestation of vitamin B12 deficiency and accounts for 20-50% of cases.

4p viwhitewolf 03-07-2023 4 3   Download

Upshaw–Schulman syndrome (USS) is an autosomal recessive disease characterized by thrombotic microangiopathies caused by pathogenic variants in ADAMTS13. We aimed to (1) curate the ADAMTS13 gene pathogenic variant dataset and (2) estimate the carrier frequency and genetic prevalence of USS using Genome Aggregation Database (gnomAD) data.

8p vihagrid 30-01-2023 7 3   Download

The enzyme involved in regulating the size of vWF (von Willebrand factor) in plasma is ADAMTS-13 (A disintegrin and metalloprotease with thrombospondin type-1 motives). Deficient proteolysis of ULvWF (ultra large von Willebrand factor) due to reduced ADAMTS-13 activity results in disseminated platelet-rich thrombi in the microcirculation characteristic of thrombotic thrombocytopenic purpura.

5p vivalanbo2711 19-03-2020 11 1   Download

(BQ) Continued part 1, part 2 of the document Inpatient medicine 2018-2019 and current practice guidelines has contents: Vertebral osteomyelitis, prosthetic joint infections, outpatient parenteral antibiotic therapy, thrombotic thrombocytopenic purpura, acute kidney injury,... and other contents. Invite you to refer.

114p thuongdanguyetan05 05-07-2019 16 1   Download

Đề tài này được thực hiện với mục tiêu mô tả áp dụng thay huyết tương trong điều trị ban xuất huyết giảm tiểu cầu huyết khối hội chứng urê huyết tán huyết (thrombotic thrombocytopenic purpura - hemolytic uremic syndrome, TTPHUS).

6p hanh_tv4 05-12-2018 49 2   Download

This woman has a combination of hemolytic anemia with fragmented RBCs on peripheral smear; thrombocytopenia; fever; neurologic symptoms; and renal dysfunction -- a classic pentad of symptoms that characterizes thrombotic thrombocytopenic purpura (TTP). Approximately 90% of patients will respond to plasmapheresis. Patient should be emergently treated with largevolume plasmapheresis. Sixty to 80 mL/kg of plasma should be removed and replaced with fresh-frozen plasma. Treatment should be continued daily until the patient is in complete remission.

330p hyperion75 21-01-2013 41 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS): a 24-year clinical experience with 178 patients

8p toshiba24 06-12-2011 53 3   Download

Thrombotic Thrombocytopenic Purpura TTP and HUS were previously considered overlap syndromes. However, in the past few years the pathophysiology of inherited and idiopathic TTP has become better understood and clearly differs from HUS. TTP was first described in 1924 by Eli Moschcowitz and characterized by a pentad of findings that include microangiopathic hemolytic anemia, thrombocytopenia, renal failure, neurologic findings, and fever. The full-blown syndrome is less commonly seen now, probably due to earlier diagnosis.

5p thanhongan 07-12-2010 74 2   Download

Fresh-Frozen Plasma FFP contains stable coagulation factors and plasma proteins: fibrinogen, antithrombin, albumin, as well as proteins C and S. Indications for FFP include correction of coagulopathies, including the rapid reversal of warfarin; supplying deficient plasma proteins; and treatment of thrombotic thrombocytopenic purpura. FFP should not be routinely used to expand blood volume. FFP is an acellular component and does not transmit intracellular infections, e.g., CMV.

5p thanhongan 07-12-2010 66 2   Download