Traditional risk factors
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Genome-wide association studies (GWAS) have identified pervasive sharing of genetic architectures across multiple immune-mediated diseases (IMD). By learning the genetic basis of IMD risk from common diseases, this sharing can be exploited to enable analysis of less frequent IMD where, due to limited sample size, traditional GWAS techniques are challenging.
17p vibransone 28-03-2024 4 2 Download
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Breast cancer patients from the indigenous Arab population present much earlier than patients from Western countries and have traditionally been underrepresented in cancer genomics studies. The contribution of polygenic and Mendelian risk toward the earlier onset of breast cancer in the population remains elusive.
14p vicwell 29-02-2024 5 1 Download
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In traditional opinion, solid pulmonary nodule suspected lung cancer should be confirmed by pathology before the operation to exclude small cell lung cancer (SCLC), considering SCLC tends to be aggressive and surgical effect in the management of SCLC remains controversial. The aim of this study was to evaluate the survival result and risk factors of postoperative unsuspected SCLC.
10p vileonardodavinci 23-12-2023 3 2 Download
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Neuroblastoma (NB) is a childhood malignant tumor,50% of high-risk NB children still have recurrence, and the long-term survival rate is very low. NB tumors expressing high levels of BDNF/TrkB are associated with poor survival outcomes.In this study, we show that the trends of serum concentration of BDNF at different growth stages after birth, and explore the relationship with NB replase.
9p vioracle 29-09-2023 3 2 Download
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Nowadays, as the global population grows, the demand for food is also becoming higher each day. Together with the rise in food demand, Muscovy duck has been gradually bred industrially as a poultry food supply along with the chicken. The change from traditional to industrial breeding poses a potential risk of pathogenic bacteria infection and antimicrobial resistance bacteria.
17p vicaptainmarvel 21-04-2023 4 2 Download
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Traditional CKD risk factors as well as HIV-related factors are major determinants of the prevalence of renal diseases among HIV patients. Few equations have been used in clinical practice for calculating creatinine clearance, however, the accuracy of these formulae in HIV patients has been different.
8p vicaptainmarvel 21-04-2023 3 2 Download
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Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNPs) as associated with colorectal cancer (CRC) risk in populations of European descent. However, their utility for predicting risk to CRC in Asians remains unknown.
7p vinarcissa 21-03-2023 7 2 Download
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Type 2 diabetes mellitus (T2DM) is becoming one of the leading causes of morbidity and mortality worldwide, including among Africans. Knowledge of the association between traditional risk factors and both diabetes and pre-diabetes, and whether these differ by age and sex, is important for designing targeted interventions. However, little is known about these associations for African populations.
11p viferrari 28-11-2022 8 3 Download
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Genome-wide association studies (GWAS) have identified hundreds of loci associated with coronary artery disease (CAD) and blood pressure (BP) or hypertension. Many of these loci are not linked to traditional risk factors, nor do they include obvious candidate genes, complicating their functional characterization.
13p vigalileogalilei 27-02-2022 14 1 Download
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Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with only traditional risk factors is still not clear. Hence, our primary aim was to summarize literature on risk prediction models including genetic variants for CRC, while our secondary aim was to evaluate the improvement of discriminatory accuracy when adding SNPs to a prediction model with only traditional risk factors.
21p vielonmusk 21-01-2022 11 0 Download
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Cardiovascular morbidity and mortality is high in patients with chronic obstructive pulmonary disease (COPD) and arterial stiffness is a potentially modifiable risk factor with added predictive value beyond that obtained from traditional risk factors.
7p vimontana2711 05-04-2021 12 2 Download
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Factors associated with reduced daily physical activity (DPA) in patients with COPD are still controversial. Physical inactivity in COPD increases risk of cardiovascular disease, frequent exacerbations, reduced health status, and increased symptoms. We hypothesised that reduced DPA in patients with COPD is independent of traditional risk factors including age and spirometry.
8p vimaine2711 26-03-2021 13 2 Download
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Rheumatoid arthritis (RA) has been associated with an increased risk of cardiovascular morbidity and mortality but this has not translated to optimal management of traditional cardiovascular risk factors such as hyperlipidemia.
8p vioregon2711 22-02-2021 11 2 Download
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Melanocortin-1 receptor (MC1R) gene variants are very common and are associated with melanoma risk, but their contribution to melanoma risk prediction compared with traditional risk factors is unknown.
13p vijennie2711 29-09-2020 18 1 Download
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Oropharyngeal Squamous Cell Carcinoma (OPSCC) is increasing in incidence despite a decline in traditional risk factors. Human Papilloma Virus (HPV), specifically subtypes 16, 18, 31 and 35, has been implicated as the high-risk etiologic agent.
10p vibaku2711 22-07-2020 10 1 Download
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Enteropathogenic Escherichia coli (EPEC) was a leading cause of infantile diarrhea in many countries. But this bacteria had never research in flours and porridges consume by infant in Côte d‟Ivoire. The aim of this study was to determine the prevalence of EPEC in maize and millet flours and porridges made traditionally. EPEC were research in 996 samples of traditional cereals products, with 404 flours and 592 porridges. These products were taken in five municipalities of Abidjan. The strains were characterized by detection of virulence factors and phylogenetic method.
15p nguaconbaynhay6 23-06-2020 8 1 Download
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The changing global climatic scenario is a serious threat to the field of plant disease management. Reckless use of traditional agrochemicals is augmenting risks of environmental and ecological hazard with a negative impact on available resources in managing plant diseases. Frequent use of toxic agrochemicals poses threat not only to the abiotic components but also are of serious concern to the biotic factors of our ecosystem. The era demands incessant exploration in the innovative and opportunistic strategies which have greater impact with minimal use in eliminating plant diseases.
6p chauchaungayxua4 18-03-2020 20 1 Download
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Survey was undertaken to assess honey production system, identify major beekeeping constraints and determine the association of potential risk factors with occurrence of honeybee diseases, predators and pests at Ganderbal district of Kashmir during summer 2018. Questionnaire survey and laboratory diagnostic methods were employed. A total of 50 beekeepers were included in the questionnaire survey and were interviewed through questionnaire survey, 64.5% had knowledge about honey bee diseases and pests.
5p quenchua2 16-12-2019 15 0 Download
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Adoption is a process of making a decision about an innovation of technology option offered to anyone. Even though we have brought about green revolution and moving for second green revolution, more than 60% of technology cannot reach the domain of farmer‟s innovation decision. So the present study takes care of adoption process of „Gobindabhog‟ famous traditional aromatic rice, to explore the process and complexity of its adoption and subsequent socialization. Aromatic rice like Gobindabhog has got social, ecological and economic importance.
7p nguaconbaynhay1 08-12-2019 17 0 Download
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Microbes are the sources of many food poisoning cases, usually due to improperly processed food and fruit juice separation by hand or juice mill. It is now commonly accepted that fruit juice consumption is a risk factor for infection with enteric pathogens. The trouble begins when certain bacteria and other harmful pathogens spores of multiply and spread in ubiquitous and environments. However, fruit juice Sample was collected from the various places of Kanpur, India and observed the highest microbial load in nutrient agar (4.3X107 ) viz., Shivrajpur, rose bengal chloramphenicol agar (2.
14p nguaconbaynhay1 04-12-2019 18 1 Download