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Transcriptional noise
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Accumulating evidence has demonstrated that long non-coding RNAs (lncRNAs) are closely associated with human diseases, and it is useful for the diagnosis and treatment of diseases to get the relationships between lncRNAs and diseases.
22p
viwyoming2711
16-12-2020
12
1
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Active protein translation can be assessed and measured using ribosome profiling sequencing strategies. Prevailing analytical approaches applied to this technology make use of sequence fragment length profiling or reading frame occupancy enrichment to differentiate between active translation and background noise, however they do not consider additional characteristics inherent to the technology which limits their overall accuracy.
6p
vioklahoma2711
19-11-2020
8
0
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Noises and artifacts may arise in several steps of the next-generation sequencing (NGS) process. Recently, an NGS library preparation method called SMART, or Switching Mechanism At the 5′ end of the RNA Transcript, is introduced to prepare ChIP-seq (chromatin immunoprecipitation and deep sequencing) libraries from small amount of DNA material, using the DNA SMART ChIP-seq Kit.
13p
vicoachella2711
27-10-2020
8
0
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Single-cell RNA sequencing (scRNA-seq) provides an effective tool to investigate the transcriptomic characteristics at the single-cell resolution. Due to the low amounts of transcripts in single cells and the technical biases in experiments, the raw scRNA-seq data usually includes large noise and makes the downstream analyses complicated.
21p
vicolorado2711
22-10-2020
8
0
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ChIP (Chromatin immunoprecipitation)-exo has emerged as an important and versatile improvement over conventional ChIP-seq as it reduces the level of noise, maps the transcription factor (TF) binding location in a very precise manner, upto single base-pair resolution, and enables binding mode prediction.
14p
vicolorado2711
22-10-2020
8
0
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Reverse engineering of transcriptional regulatory networks (TRN) from genomics data has always represented a computational challenge in System Biology. The major issue is modeling the complex crosstalk among transcription factors (TFs) and their target genes, with a method able to handle both the high number of interacting variables and the noise in the available heterogeneous experimental sources of information.
28p
vicolorado2711
22-10-2020
20
2
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Từ vựng tiếng Anh cơ bản (2) .Tiếp theo phần 1, phần 2 là các từ vựng tiếng Anh quen thuộc. Mời các bạn xem tiếp bài viết sau nhé. Word Transcript Class Meaning Example The children are always always / l.we z/ adv luôn luôn making noise.Bọn trẻ con luôn luôn ầm ĩ. I think I am the best am /æm/ v là student in my class.
6p
oishithetgiay
19-06-2013
185
30
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We address the task of unsupervised topic segmentation of speech data operating over raw acoustic information. In contrast to existing algorithms for topic segmentation of speech, our approach does not require input transcripts. Our method predicts topic changes by analyzing the distribution of reoccurring acoustic patterns in the speech signal corresponding to a single speaker. The algorithm robustly handles noise inherent in acoustic matching by intelligently aggregating information about the similarity profile from multiple local comparisons. ...
8p
hongvang_1
16-04-2013
49
1
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Self-sustained oscillations are perhaps the most studied objects in science. The accomplishment of such a task reliably and accurately requires the presence of specific control mechanisms to face the presence of variable and largely unpredictable environmental stimuli and noise.
8p
media19
06-03-2013
38
3
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals...
0p
thulanh21
12-11-2011
46
1
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Verbatim Notes Typed verbatim notes (also known as “approximate” transcripts) are a nice alternative since they contain valuable details and quotes without the extra noise included in an audio or video transcript. If you go with this approach, instruct the note taker to focus on the interview dialogue. The note taker should not be interpreting and adding commentary along the way—interpretation happens after the session. STILL CAMERA Researchers should always bring a still camera to user interviews. It is valuable for capturing the participant’s computer setup and context of use.
10p
yukogaru13
30-11-2010
2050
5
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