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Treatment of Staphylococcus aureus in vitro
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The bactericidal activity of an antimicrobial drug is generally assessed by in vitro bacterial time-kill experiments which do not include any components of the immune system, even though the innate immunity, the primary host defence, is probably able to kill a large proportion of pathogenic bacteria in immunocompetent patients.
10p
vidarwin
23-02-2022
15
1
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The isolated phages had plaques with 3–5 mm diameters and a distinct translucent spreading halo. The morphological phage particles were cubic nucleocapsid with 65–75 nm across with short contractile tails. The supplemented cosmetic phages reduced the bacterial growth to 95.45%, compared with free phages and non-supplemented cosmetic 86.1% and 77% respectively.
6p
schindler
30-12-2021
5
0
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Methicilin–resistant Staphylococcus aureus (MRSA) is a common cause of serious nosocomial infections with limited options for treatment due to its known resistance to many antibiotics. Knowledge guided antibiotic combination therapy can be of great benefit in fighting this superbug. The aim of this study was to evaluate the combined activity of penicillin G (A) and gentamicin (B) against clinical isolates of methicillin resistant Staphylococcus aureus.
10p
nguaconbaynhay7
15-08-2020
24
1
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Daptomycin is an important drug used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. A high dose of daptomycin is indicated for an MRSA infection with a minimum inhibitory concentration (MIC) of 1 mg/L for daptomycin.
6p
vimax2711
27-03-2020
15
0
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Mastitis is the inflammation of the mammary gland and udder tissue, and is a major endemic disease of dairy cattle. It is also the most costly disease to the dairy industry. Bovine mastitis caused by Escherichia coli (E.coli) and Staphylococcus aureus can ranges from being a subclinical infection of the mammary gland to a severe systemic disease. Antimicrobial resistance is generally not a limiting factor for treatment, but it should be monitored to detect changes in resistance profiles.
7p
chauchaungayxua4
18-03-2020
10
1
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Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading pathogens for hospital and community-acquired infections. Increased use of Vancomycin has resulted in the emergence of MRSA with reduced susceptibility to Vancomycin. The emergence of Vancomycin-intermediate or resistant S. aureus has created the need for other anti MRSA antibiotics. To isolate the Staphylococcus aureus from various clinical samples, determine the prevalence of MRSA and to assess the in-vitro susceptibility of Daptomycin against MRSA isolates.
8p
chauchaungayxua3
07-02-2020
13
0
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This in-vitro study evaluates the antibacterial &antifungal action of aqueous & alcoholic extracts of new herbal vaginal formulation containing equal amounts of Symplocos racemosa Roxb. and Ficus glomerata Roxb. stem barks against gram positive and gram negative bacteria and candid fungus by using the methods of zone of inhibition and minimum inhibition concentration (MIC) to assess its efficacy in treating vaginitis. During phytochemical analysis, alkaloids, flavonoids, tannins and carbohydrates were found to be present in both extracts.
11p
kethamoi2
15-12-2019
12
0
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Staphylococcus aureus and Pseudomonas aeruginosa are part of the human microbiota and are also important bacterial pathogens, for which therapeutic options are lacking nowadays. The combined administration of corticosteroids and antimicrobials is commonly used in the treatment of infectious diseases to control inflammatory processes and to minimize potential toxicity of antimicrobials, avoiding sequelae.
7p
kequaidan1
16-11-2019
22
0
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Statins inhibit cholesterol synthesis and are prescribed to those at high risk of developing cardiovascular disease. The widespread use of these drugs has promoted interest in their other effects: this study shows that statins affect phagocyte functions. Pre-treatment with statins increased the capacity of human neutrophils and macrophages to kill various bacteria in vitro, but paradoxically, statins decreased the ability of neutrophils to phagocytose Staphylococcus aureus or induce the oxidative burst....
0p
camchuong_1
11-12-2012
66
2
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