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Triple-negative cancer
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Some studies have shown that Immune checkpoint inhibitors (ICIs) have a favorable efcacy in advanced triple negative breast cancer (TNBC) patients, but the results are controversial in neoadjuvant chemotherapy (NACT) stage. The purpose of this study is to evaluate the efcacy and safety after NACT plus ICIs in early TNBC patients.
10p
vimahuateng
26-11-2021
12
1
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Triple-negative breast cancer (TNBC) is associated with an aggressive clinical course due to the lack of therapeutic targets. Therefore, identifying reliable prognostic biomarkers and novel therapeutic targets for patients with TNBC is required.
11p
vimoscow2711
29-08-2020
6
0
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In breast cancer, p63 expression has been found predominantly in basal-A (epithelial-type) triplenegative breast carcinomas (TNBC). To investigate the functional role of p63 in basal-A TNBC, we created MDA-MB468 cell lines with inducible expression of the two major N-terminal p63 isoforms, TAp63α and ΔNp63α.
12p
vimale2711
25-08-2020
9
1
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Triple-negative breast cancer (TNBC) is the malignancy with the worst outcome among all breast cancer subtypes. We reported that ETV1 is a significant oncogene in TNBC tumourigenesis. Consequently, investigating the critical regulatory microRNAs (miRNAs) of ETV1 may be beneficial for TNBC targeted therapy.
13p
vimanama2711
30-07-2020
6
1
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Triple-negative breast cancer (TNBC) comprises a heterogeneous group of diseases which are generally associated with poor prognosis.
9p
vimanila2711
25-06-2020
8
1
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This study aimed to investigate the clinical utility of serum and histological MMP-9 detection during neoadjuvant chemotherapy (NAC) for triple-negative breast cancer (TNBC).
8p
vimanila2711
25-06-2020
9
2
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A higher density of tumor-infiltrating lymphocytes (TILs) can lead to greater therapeutic effects and improved prognoses in cancer treatment. Similar results have been observed in breast cancer, particularly in triplenegative breast cancer (TNBC) and human epidermal growth factor receptor 2-enriched breast cancer.
10p
vikuala271
13-06-2020
8
1
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The objective of this systematic review and meta-analysis was to determine the prognostic value of total tumor-infiltrating lymphocytes (TILs) and subtypes of TILs (CD4+ , CD8+ , and FOXP3+ ) in triple-negative breast cancer (TNBC).
15p
vijakarta2711
09-06-2020
28
0
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