Triterpenoids and steroids

“Linh chi” - the Vietnamese name for Ganoderma can be used in the prevention and treatment of various types of disease. Various compounds have been isolated from the fruiting bodies, spores, gills, and mycelia of many Ganoderma mushrooms. Ganoderma contains many bioactive natural components, including triterpenes, steroid, polysaccharides, proteins, and unsaturated fatty acids.

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Bruguiera cylindrica (Rhizophoracea), distributed in the Southeast Asia, has been used as a traditional medicine in the treatment of diarrhea and healing of wounds. Some triterpenoids and steroids were isolated from the dried leaves of Bruguiera cylindrica, collected at Can Gio mangrove forest, Ho Chi Minh City, including lupeol (1), 3βhydroxyoleana-9(11),12-diene (2), a mixture of stigmasterol (3a) and -sitosterol (3b), cholesta-4-ene-3-one (4) and 3β-hydroxycholesta-5-ene-7-one (5).

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Chemical investigation of the ethyl acetate extract of the lichen Lobaria orientalis, Lobariaceae, collected in Vietnam, afforded six known compounds, including four triterpenoids, zeorin (1), 16β-acetoxyhopane-6α,22-diol (2), retigeric acid A (3), retigeric acid B (4), together with two steroids, ergosterol-5α,8α-peroxide (5) and cerevisterol (6).

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