Tumor staging
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For patients with early-stage cervical cancer without high-risk factors, there is no consensus regarding the optimal postoperative treatment regimen and whether postoperative concurrent radiochemotherapy (CCRT) is superior to radiotherapy (RT) alone.
12p vishanshan 27-06-2024 1 1 Download
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Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes migration and invasion of lung adenocarcinoma cells (LAC), during which LXR as a 25-HC receptor plays an important role.
14p vishanshan 27-06-2024 3 1 Download
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Clear cell renal cell carcinoma (ccRCC) is associated with a high prevalence of cancer-related deaths. This study aims to develop an efficient nomogram model for stratifying and predicting the survival of ccRCC patients based on tumor stage.
13p vishanshan 27-06-2024 1 1 Download
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One-third of diffuse large B-cell lymphoma (DLBCL) patients suffer relapse after standard treatment. Eukaryotic initiation factor 3a (eIF3a) is a key player in the initial stage of translation, which has been widely reported to be correlated with tumorigenesis and therapeutic response. This study aimed to explore the biological role of eIF3a, evaluate its prognostic and therapeutic potential in DLBCL.
16p vishanshan 27-06-2024 2 1 Download
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Bone tumors account for approximately 6% of all cancers in children. Malignant bone tumors, commonly occurring in children and adolescents, are associated with high mortality and morbidity. The overall survival of children with primary malignant bone tumors is affected by the stage of disease, time of diagnosis, and treatment response.
10p vishanshan 27-06-2024 1 1 Download
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Despite inter-study heterogeneity, our meta-analysis showed a higher rate of metastatic tumors at diagnosis after the pandemic. The burden of social distancing policies might explain those results, as patients may have delayed seeking care.
13p vishanshan 27-06-2024 2 1 Download
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Circulating total insulin-like growth factor-I (IGF-I) is an established risk factor for prostate cancer. However, only a small proportion of circulating IGF-I is free or readily dissociable from IGF-binding proteins (its bioavailable form), and few studies have investigated the association of circulating free IGF-I with prostate cancer risk.
10p vishanshan 27-06-2024 2 1 Download
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This study aims to develop a nomogram integrating inflammation (NLR), Prognostic Nutritional Index (PNI), and EBV DNA (tumor burden) to achieve personalized treatment and prediction for stage IVA NPC. Furthermore, it endeavors to pinpoint specific subgroups that may derive significant benefits from S-1 adjuvant chemotherapy.
16p vishanshan 27-06-2024 1 1 Download
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Emerging evidence suggests the dysregulation of long non-coding RNAs (lncRNAs) involved in pancreatic cancer (PC). However, the function of LINC00930 in PC has not been elaborated. In this study, we found that LINC00930 was significantly down-regulated in PC cell lines and tissues, and associated with tumor size, lymphatic metastasis, TNM stage and poor prognosis.
14p vishanshan 27-06-2024 2 1 Download
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In oral squamous cell carcinoma (OSCC), the tumor-node-metastasis (TNM) staging system is a significant factor that influences prognosis and treatment decisions for OSCC patients. Unfortunately, TNM staging does not consistently predict patient prognosis and patients with identical clinicopathological characteristics may have vastly diferent survival outcomes.
21p vikoch 27-06-2024 1 1 Download
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Pancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of cancer-related deaths globally. Its incidence is notably increasing. This poor prognosis is primarily due to late-stage diagnosis (approximately 70% to 80% of patients are diagnosed at an advanced stage), aggressive tumor biology, and low sensitivity to chemotherapy.
10p vikoch 27-06-2024 3 1 Download
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Gastric cancer is one of the most common tumors worldwide, and most patients are deprived of treatment options when diagnosed at advanced stages. PRDM14 has carcinogenic potential in breast and non-small cell lung cancer. however, its role in gastric cancer has not been elucidated.
13p vikoch 27-06-2024 1 1 Download
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Liquid biopsy can detect circulating cancer cells or tumor cell-derived DNA at various stages of cancer. The fluid from these biopsies contains extracellular vesicles (EVs), such as apoptotic bodies, microvesicles, exomeres, and exosomes.
15p vikoch 27-06-2024 1 1 Download
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To evaluate the results of soft tissue defect treatment with ALT composite flaps in covering secondary soft tissue defects after radical tumors resection. Method: From October 2017 to April 2023, we performed a series of 10 single-stage surgeries using composite anterior lateral thigh flap to cover secondary tissue defects in 2 cases covered Achilles tendon defects and 8 cases covered secondary defects after resection of tumors.
6p viambani 21-05-2024 2 1 Download
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Phenotypic changes during cancer progression are associated with alterations in gene expression, which can be exploited to build molecular signatures for tumor stage identification and prognosis. However, it is not yet known whether the relative abundance of transcript isoforms may be informative for clinical stage and survival.
14p vioraclene 31-03-2024 5 2 Download
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Cancer recurrence after tumor resection in early-stage non-small cell lung cancer (NSCLC) is common, yet difficult to predict. The lung microbiota and systemic immunity may be important modulators of risk for lung cancer recurrence, yet biomarkers from the lung microbiome and peripheral immune environment are understudied. Such markers may hold promise for prediction as well as improved etiologic understanding of lung cancer recurrence.
17p viellison 28-03-2024 2 1 Download
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To describe imaging characteristics of rectal cancer on high-resolution T2-weighted MRI in predicting local staging of rectal cancer. A cross-sectional descriptive study aimed at evaluating the sensitivity, specificity, accuracy, and correlation coefficient of MRI in staging T (tumor) and N (lymph node involvement) in patients with rectal cancer.
6p virichard 28-03-2024 2 1 Download
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Ebook "The biology of gastric cancers" represents the very first volume devoted to the subject of the basic biology of gastric cancer. Although there were major achievements 30–40 years ago in the description of the histopathology of stomach tumors and the preneoplastic conditions that preceded these lesions, it was of course the pioneering (and Nobel prize– winning) studies involving the discovery of Helicobacter pylori by Marshall and Warren that set the stage for the more recent insights on the role of chronic inflammation and cancer.
654p cotieubac1004 15-03-2024 0 0 Download
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Desmoplastic small round cell tumor is a rare malignancy with poor prognosis, affecting young male patients. It frequently presents as a large abdominal mass with widespread peritoneal involvement at diagnosis. In late stages, metastases may be present.
6p vilazada 31-01-2024 4 2 Download
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Part 1 book "Atlas for the diagnosis of tumors in the dog and cat" includes content: Overview of grading and staging; selected lesions of the head and neck; selected lesions of the limbs, paws, and digits.
131p muasambanhan02 25-12-2023 5 2 Download