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Tumour growth
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Evaluation of human epidermal growth factor receptor 2 (HER2) overexpression caused by erbb2 receptor tyrosine kinase 2 (ERBB2) amplification (AMP) by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) is essential for treating unresectable metastatic gastric cancer (GC).
13p
vikoch
27-06-2024
1
1
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In ebook "Developmental biology of neoplastic growth" tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest.
263p
tracanhphuonghoa1007
22-04-2024
4
2
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Part 1 book "BSAVA manual of canine and feline musculoskeletal disorders - A practical guide to lameness and joint disease" includes content: Normal locomotion, lameness examination, imaging, sampling and laboratory investigation, the normal joint, arthritis, diseases and disorders of bone, disturbances of growth and bone development, muscle, tendon and ligament injuries, diseases of muscle and the neuromuscular junction, tumours of the musculoskeletal system, neurological causes of lameness, principles of orthopaedic surgery.
208p
muasambanhan04
11-01-2024
6
1
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Part 1 book "Animal oncology" includes content: Certain terminologies used in relation with neoplasm; nomenclature and classification of tumours; etiology of neoplasms – intrinsic and extrinsic factors; radiation induced carcinogenesis; chemical carcinogenesis; parasitic carcinogenesis; bacterial carcinogenesis; viral carcinogenesis; tumour diagnosis; biology of tumour growth; tumour spread; tumour immunity; tumour effects; paraneoplastic syndrome.
88p
muasambanhan04
11-01-2024
4
1
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The histopathological growth patterns (HGPs) are a prognostic and predictive biomarker in colorectal cancer liver metastasis (CRLM). This study evaluates the relationship between the HGP and primary colorectal cancer (CRC) histopathology.
15p
vialfrednobel
23-12-2023
6
3
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Hexokinase 2 (HK2) is an enzyme that catalyses the conversion of glucose to glucose-6-phosphate, which has been found to be associated with malignant tumour growth. However, the potential immunological and clinical significance of HK2, especially in terms of prognostic prediction for patients with glioma, has not been fully elucidated.
20p
vialfrednobel
23-12-2023
6
3
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Colorectal cancer is a common malignant tumour. Invasive growth and distant metastasis are the main characteristics of its malignant biological behaviour, and they are also the primary factors leading to death in colon cancer patients. Atovaquone is an antimalarial drug, and its anticancer effect has recently been demonstrated in several cancer models in vitro and in vivo, but it has not been examined in the treatment of colorectal cancer.
13p
vialfrednobel
23-12-2023
10
2
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Part 1 book "Clinical equine oncology" includes content: Introduction, the challenges and problems of equine oncological practice, tumour nomenclature, biology of tumour growth, clinical effects of cancer in horses; paraneoplastic syndromes; principles of diagnosis; pathological methods in equine oncology; principles of oncological therapy.
427p
muasambanhan01
11-12-2023
4
2
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Glioblastoma (GB) is the most aggressive of all primary brain tumours and due to its highly invasive nature, surgical resection is nearly impossible. Patients typically rely on radiotherapy with concurrent temozolomide (TMZ) treatment and face a median survival of~14 months.
14p
visharma
20-10-2023
7
2
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3D culture is increasingly used in cancer research, as it allows the growth of cells in an environment that mimics in vivo conditions. Metastases are the primary cause of morbidity and mortality in cancer patients, and solid tumour metastases are mostly located in lymph nodes.
12p
vioracle
29-09-2023
3
2
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High dose unilobar radioembolization (also termed ‘radiation lobectomy’)—the transarterial unilobar infusion of radioactive microspheres as a means of controlling tumour growth while concomitantly inducing future liver remnant hypertrophy—has recently gained interest as induction strategy for surgical resection.
9p
vioracle
29-09-2023
2
2
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Desmoid tumors are rare lesions. Although they demonstrate tumor characteristics, such as infiltrative growth and tendency towards local recurrence, they lack the ability to metastasize. To date, the cause of desmoid tumors is unknown. They can occur in both sexes, but predominant slightly in women, including nulliparous women, of reproductive age, but mostly during and after pregnancy.
4p
vigamora
23-05-2023
11
3
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Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) provide a better prognosis in EGFR-mutant non-small cell lung cancer (NSCLC). Nevertheless, the outcome of leptomeningeal metastasis (LM) remains poor. In addition, due to limited access to intracranial tumour tissue, gene alterations associated with leptomeningeal metastasis from lung adenocarcinoma (LM-LUAD) are unclear.
8p
visusanwojcicki
28-06-2022
5
2
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Rivoceranib, a novel tyrosine kinase inhibitor, exhibits anti-tumour effects by selectively blocking vascular endothelial growth factor receptor-2 (VEGFR2) in cancer cells. Recently, the therapeutic effects of rivoceranib on solid tumours have been elucidated in human patients.
12p
vidarwin
22-02-2022
10
1
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The control of energy metabolism is fundamental for cell growth and function and anomalies in it are implicated in complex diseases and ageing. Metabolism in yeast cells can be manipulated by supplying different carbon sources: Yeast grown on glucose rapidly proliferates by fermentation, analogous to tumour cells growing by aerobic glycolysis, whereas on non-fermentable carbon sources metabolism shifts towards respiration.
18p
vialfrednobel
29-01-2022
11
0
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The prognosis of oral squamous cell carcinoma (OSCC) patients is difficult to predict or describe due to its high-level heterogeneity and complex aetiologic factors. Ferroptosis is a novel form of iron-dependent cell death that is closely related to tumour growth and progression. This study aims to clarify the predictive value of ferroptosis-related genes (FRGs) on the overall survival(OS) of OSCC patients.
16p
vimahuateng
26-11-2021
16
1
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In clear cell renal cell carcinoma, 80% of cases have biallelic inactivation of the VHL gene, leading to constitutive activation of both HIF1α and HIF2α. As HIF2α is the driver of the disease promoting tumour growth and metastasis, drugs targeting HIF2α have been developed. However, resistance is common, therefore new therapies are needed.
12p
vimahuateng
26-11-2021
8
1
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EGFR mutations are routinely explored in lung adenocarcinoma by sequencing tumoral DNA. The aim of this study was to evaluate a fluorescent-labelled erlotinib based theranostic agent for the molecular imaging of mutated EGFR tumours in vitro and ex vivo using a mice xenograft model and fibred confocal fluorescence microscopy (FCFM).
9p
vimontana2711
05-04-2021
17
1
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Desmoid-type fibromatosis (DF) is a aggressive (myo) fibroblastic neoplasm with an infiltrative growth and a tendency to local recurrence. Resection of the tumour and/or radiation were proposed as principal treatment. The aim of this retrospective study was to analyze the local control rates focusing on the effect of surgical margins and radiotherapy.
7p
vitennessee2711
02-02-2021
9
2
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A six year old cow with growth on the left horn, with foul smell and bleeding was presented to clinics. On clinical examination the horn growth is characterised by granulation tissue at the base of the horn with offensive odour and was spongy, greyish white cauliflower like having rough and verrucous surface and was diagnosed as horn cancer. The horn tumor was removed surgically from the base and the animal was recovered uneventfully. The histopathology of the tumour revealed the squamous cell carcinoma.
4p
angicungduoc8
07-11-2020
10
1
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