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Type II diabetes
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Diabetes mellitus is a chronic disease that requires long term medical attention both to limit the development of its devastating complications and manage them when they occur. This study was designed to assess the effect of glycaemic control on the serum lipid profile of type II diabetic patients in the university college hospital Ibadan, Oyo State.
5p
viisac
23-09-2023
2
2
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Using the natural agents with inhibitory activity against digestive enzymes α-glucosidase and αamylase capable of hydrolyzing carbohydrates into glucose to reduce blood glucose levels in the blood is one of the effective strategies to control diabetes, especially type II diabetes. α-Mangostin (AMG) was proven to have strong biological activities, such as antifungal, antibacterial, anti-inflammatory, anti-cancer.
9p
vimulcahy
18-09-2023
2
2
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Starch is an important class of macromolecules for human nutrition. However, its rapid digestibility leads to a high amount of glucose released into the blood and contributes to a high risk of obesity and type II diabetes.
8p
vihermione
06-01-2023
10
3
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To find the association between polypharmacy and health consequences in type 2 diabetes mellitus (T2DM). Materials and Methods: 50 patients with multiple drugs (two or more) and morbidity, glycemic control, macrovascular complications, hospitalization, gastrointestinal disorders, cost of medicine were studied.
9p
viporsche
28-10-2022
12
3
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The purpose of this study is to analyze the effect of body mass index (BMI) on patients with concurrent colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM). Methods: Patients who underwent primary radical CRC surgery from Jan 2011 to Jan 2020 were retrospectively collected. The perioperative information, overall survival (OS) and disease-free survival (DFS) were compared between the higher BMI group and the lower BMI group.
9p
visusanwojcicki
28-06-2022
11
3
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This study is thus an attempt to determine the associations among sarcopenia, frailty, and the SFT in diabetic patients and non-diabetic controls to provide a more comprehensive understanding of such associations in future evaluations of T2DM in older individuals.
10p
vinobelprisen
26-03-2022
14
3
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The therapeutic applications of 1,2,4-triazoles motivated us to synthesize some new derivatives. Two series of S -substituted derivatives (8a–8j, 12a–12i) of 5-{1-[(4-chlorophenyl)sulfonyl]-3-piperidinyl}-4-phenyl-4H -1,2,4-triazol3-thiol (6) have been synthesized and evaluated for their biological potential.
20p
tudichquannguyet
29-11-2021
8
1
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In this study, using the connectivity map program, it was determined that metformin and tolbutamide used in the treatment of type II diabetes had the potential to inhibit Rho kinase. In the experimental results to confirm this data, it has been shown that metformin and tolbutamide decrease the cell area within 24 h and metformin inhibits the activation of Rho kinase in MCF-7 cells. These results indicate that metformin, which is used in the treatment of type II diabetes, acts as a ROCK inhibitor.
11p
thiencuuchu
27-11-2021
15
1
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Biological networks describes the mechanisms which govern cellular functions. Temporal networks show how these networks evolve over time. Studying the temporal progression of network topologies is of utmost importance since it uncovers how a network evolves and how it resists to external stimuli and internal variations.
16p
visilicon2711
20-08-2021
7
1
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Rad is the prototypic member of a subfamily of Ras-related small G-proteins and is highly expressed in the skeletal muscle of patients with type II diabetes. Our previous microarray analysis suggested that Rad may mediate fracture nonunion development.
9p
vivermont2711
28-01-2021
7
1
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Intervertebral disc degeneration in mice with type II diabetes induced by leptin receptor deficiency
The leptin receptor-deficient knockout (db/db) mouse is a well-established model for studying type II diabetes mellitus (T2DM). T2DM is an important risk factor of intervertebral disc degeneration (IVDD). Although the relationship between type I diabetes and IVDD has been reported by many studies, few studies have reported the effects of T2DM on IVDD in db/db mice model.
10p
vipalau2711
30-12-2020
16
2
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The metabolic syndrome refers to the co-occurrence of or clustering of several known cardiovascular risk factors, including insulin resistance, abdominal adiposity, atherogenic dyslipidemia and endothelial dysfunction. These conditions are interrelated and share underlying mechanisms and pathways. It identifies a subgroup of patients with shared pathophysiology who are at high risk of developing cardiovascular disease, hypertension and type II diabetes.
6p
trinhthamhodang9
16-12-2020
12
2
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We explored if known risk factors for pancreatic cancer such as type II diabetes and chronic inflammation, influence the pathophysiology of an established primary tumor in the pancreas and if administration of metformin has an impact on tumor growth.
13p
vialabama2711
21-09-2020
14
0
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The present study was aimed for studying gross and histopathological changes in various organs of STZ-NAD induced Type –II diabetic rat model. In diabetic group rats, the gross changes included congestion in liver, kidneys, heart and brain, atrophic changes in liver, heart, pancreas, spleen, thymus, testes and epididymes, edematous mesenteric lymph nodes and ulcerations in gastrointestinal tract in comparison to control group.
6p
angicungduoc5
14-06-2020
17
0
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Glycemic response, a trait that is tedious to be assayed in cereal staples, has been identified as a factor correlated with alarmingly increasing prevalence of Type II diabetes.
13p
vihashirama2711
21-05-2020
14
0
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Resistin (Retn) is a cytokine which has a controversial physiological role regarding its involvement with obesity and type II diabetes mellitus.
10p
viuchiha2711
21-04-2020
13
1
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Diabetic retinopathy (DR) is a common microvascular complication in both type I and type II diabetes. Several previous reports indicated the serum centration of some secretary factors were highly associated with DR. Therefore, we hypothesis regulatory SNPs (rSNPs) genotype in secretary factors may alter these gene expression and lead to DR.
7p
viwashington2711
04-12-2019
11
1
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Glipizide is antidiabetic drug for type II diabetic. In this paper, the process of synthesis glipizide from 5-methylpyrazine-2-carboxylic acid through two steps, yield 60 % is introduced.
6p
viengland2711
23-07-2019
16
0
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Obesity is a central feature of the metabolic syndrome and is associated with increased risk for insulin resistance and type II diabetes. Here, we investigated the contribution of human apoliprotein E3 and mouse apoli-protein E to the development of diet-induced obesity in response to western-type diet. Our data show that apolipoprotein E contributes to the development of obesity and other related metabolic disorders, and that human apolipoprotein E3 is more potent than mouse apolipoprotein E in promoting obesity in response to western-type diet. ...
14p
research12
29-04-2013
43
2
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Inhibitors targeting pancreatic a-amylase and intestinal a-glucosidases delay glucose production following digestion and are currently used in the treatment of Type II diabetes. Maltase-glucoamylase (MGA), a family 31 glycoside hydrolase, is ana-glucosidase anchored in the membrane of small intestinal epithelial cells responsible for the final step of mammalian starch digestion leading to the release of glucose.
11p
inspiron33
26-03-2013
43
3
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