Tyrosinase inhibitory activity

The present study investigated the phytochemical and biological properties of the rhizomes C. aromatica. From the CHCl3 extract of C. aromatic rhizomes, six known compounds, including (-)-hannokinol, (3R,5R)-3,5-diacetoxy-1,7-bis(4- hydroxyphenyl)heptane, naringenin, 2-(4- (hydroxymethyl)phenyl)propan-2-ol, 5-hydroxymethylfurfural, and bisacurone, were isolated. All compounds were tested on the biological inhibitory activities against tyrosinase, αglucosidase, and urease. It was the first time all compounds were isolated from rhizomes of C. aromatica Salisb.

6p dianmotminh02 03-05-2024 4 3   Download

The objectives of the thesis: Study on chemical constituents of three Trichosanthes species (T. baviensis, T. anguina, and T. kirilowii) grown in Vietnam; evaluation of cytotoxic and tyrosinase enzyme inhibitory activities of isolated compounds from the above mentioned Trichosanthes species.

14p capheviahe26 25-01-2021 18 3   Download

Usnic acid isolated from lichen was a potential bioactivity compound. It has a broad spectrum bioactivity, including antiviral, anti-inflammatory, anticancer… However, low solubility in water limited its application. Many researchs have done to overcome the restriction. Recent results showed that usnic acid derivatives bearing triazole, enamine, pyrazole and benzylidene groups had strong antiviral and anticancer activities. Thus, investigation of usnic acid derivatives synthesis was an attractive aspect due to the diversity of bioactivities of usnic acid derivatives.

8p larachdumlanat127 02-01-2021 6 2   Download

The methanol extract of P. palatiferum (Nees) Radlk. leaves exhibited a moderate inhibitory effect on the L-3,4-dihydroxyphenylalanine (L-DOPA) oxidase activity of tyrosinase in the melanin biosynthesis pathway. Further study may lead to new bioactive compounds from ethyl acetate and n-hexane fractions.

11p tamynhan5 10-12-2020 28 2   Download

This fraction showed the highest antioxidant activity by dose-dependent free radical scavenging action (IC50 69.50 ± 1.55 µg/mL). R. tomentosa leaf extracts, especially the n-hexane fraction, also exhibited strong antimicrobial activity against Gram-negative and Gram-positive bacteria and fungi as well as moderate inhibitory effect on L-DOPA (L-3,4-dihydroxyphenylalanine) oxidase activity of tyrosinase in the melanin biosynthesis pathway.

9p tamynhan8 04-11-2020 13 1   Download

Brown seaweeds, particularly Sargassum genus, contain large amount of polysaccharides, such as alginate and fucoidan, which are widely applied to related health care approaches. Obviously, this genus is a potential alternative resource for cosmetic industry with its extract gained a great deal of biochemical composition and bioactivity.

7p shiwo_ding7 05-06-2019 24 0   Download