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Upper urinary tract tumor
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Periostin is an extracellular matrix protein that has been known to be implicated in fibrillogenesis and cell migration, including cancer metastasis. Periostin overexpression in cancer cells and/or intervening stroma is usually related to tumor progression and poor patient outcomes in various human cancers; however, its role in urothelial carcinoma, especially upper urinary tract urothelial carcinomas (UTUCs), remains inconclusive.
10p
vikolindagrabar
27-07-2022
2
2
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Upper tract urothelial carcinoma (UTUC) is a tumor with sizable metastases and local recurrence. It has a worse prognosis than bladder cancer. This study was designed to investigate the urinary potential tumor markers of UTUC.
13p
virose2711
24-09-2020
7
0
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Activation of Rho, one of the small GTPases, and its major downstream target Rho-kinase (ROCK) promotes the development and metastasis of cancer. We previously showed that elevation of Rho and ROCK expression was associated with tumor invasion, metastasis, and an unfavorable prognosis in patients with urothelial cancer of the bladder or upper urinary tract.
12p
virose2711
22-09-2020
13
1
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There is growing evidence that the transcription factor nuclear factor E2-related factor 2 (Nrf2) is the major participant in regulating antioxidants and pathways for detoxifying reactive oxygen species (ROS), as well as having a vital role in tumor proliferation, invasion, and chemoresistance.
11p
vibaku2711
22-07-2020
9
2
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Congenital abnormalities of the kidney and urinary tract are common. In particular, the duplicated collecting system is one of the most common kidney abnormalities, but most are asymptomatic. The pathogenesis of these abnormalities is also known very little and some pathogenic genes are thought to be related.
5p
vistockholm2711
13-12-2019
16
1
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Urology is currently the most rapidly expanding surgical superspecialty. The reason for this exponential propulsion of this field, especially over the last two decades, is the dual role of scientific breakthroughs and the successful coupling of engineering and technology for diagnostics and treatment. The role of minimally invasive approaches to surgical extirpation and reconstruction has been unprecedented and paramount. Not only is there rapid development within each substrata of urology but these developments are continuously evolving....
88p
camchuong_1
10-12-2012
46
2
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