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Vaccinia virus
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Part 2 book "Vaccine technologies for veterinary viral diseases methods and protocols" includes content: Generation of recombinant modified vaccinia virus ankara encoding VP2, NS1, and VP7 proteins of bluetongue virus, generation of recombinant capripoxvirus vectors for vaccines and gene knockout function studies,...and other contents.
130p
oursky05
20-09-2023
3
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Cancer is a leading cause of mortality for both humans and dogs. As spontaneous canine cancers appear to be relevant models of human cancers, developing new therapeutic approaches could benefit both species. Oncolytic virotherapy is a promising therapeutic approach in cancer treatment.
13p
vigandhi
23-02-2022
5
1
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Vaccination has transformed public health, most notably including the eradication of smallpox. Despite its profound historical importance, little is known of the origins and diversity of the viruses used in smallpox vaccination. Prior to the twentieth century, the method, source and origin of smallpox vaccinations remained unstandardised and opaque. We reconstruct and analyse viral vaccine genomes associated with smallpox vaccination from historical artefacts.
11p
viarchimedes
26-01-2022
9
0
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JX594 is an oncolytic poxvirus derived from Wyeth strain vaccinia virus. We reported the presentation of cutaneous and mucosal pustules containing laboratory-confirmed JX594 in a patient following injection of JX594.
3p
vimoscow2711
29-08-2020
11
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Oncolytic virotherapy is an upcoming treatment option for many tumor entities. But so far, a first oncolytic virus only was approved for advanced stages of malignant melanomas.
13p
vidhaka2711
31-07-2020
12
1
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In human vaccine manufacturing some pathogens such as Modified Vaccinia Virus Ankara, measles, mumps virus as well as influenza viruses are still produced on primary material derived from embryonated chicken eggs.
14p
viuchiha2711
21-04-2020
12
0
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(BQ) Continued part 1, part 2 of the document Pathology of lymph node (Fourth edition) has contents: Vaccinia lymphadenitis, measles lymphadenitis, human immunodeficiency virus lymphadenitis, ordinary bacterial lymphadenitis, cat-scratch lymphadenitis, syphilitic lymphadenitis, lymphogranuloma venereum lymphadenitis,…. And other contents. Invite you to refer.
389p
thuongdanguyetan06
06-06-2019
13
1
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Hu-K4 is a human protein homologous to the K4L protein of vaccinia virus. Due to the presence of two HKD motifs, Hu-K4 was assigned to the family of Phospholipase D proteins although so far no catalytic activity has been shown. The Hu-K4 mRNA is found in many human organs with highest expression levels in the central nervous system. We extended the ORF of Hu-K4 to the 5¢ direction. As a consequence the protein is 53 amino acids larger than originally predicted, now harbouring a putative transmembrane domain....
0p
awards
06-04-2013
35
1
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Anti-poxvirus therapies are currently limited to cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine], but drug-resistant strains have already been characterized. In the aim of finding a new target, the thymidy-late (TMP) kinase from vaccinia virus, the prototype of Orthopoxvirus, has been overexpressed inEscherichia coliafter cloning the gene (A48R).
12p
dell39
27-03-2013
37
3
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The molecular definition of tumor antigens, costimulatory signals, and the possibility to genetically engineer tumor cells as well as simple protocols for efficient isolation and preparation of dendritic cells (DC) renew the interest in tumor immunotherapy and vaccination, in particular. Engineering of tumor cells with the gene of a particular cytokine is a way of releasing that cytokine at the tumor site. In contrast to bolus administration, it provides a constant supply of cytokine.
634p
tom_123
15-11-2012
74
5
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The poxvirus family includes a large number of related DNA viruses that infect various vertebrate hosts. The poxviruses responsible for infections in humans, along with the main manifestations of these infections, are listed in Table 176-1. Infections with orthopoxviruses—e.g., smallpox (variola major) virus (Chap. 214) or the zoonotic monkeypox virus—can result in systemic, potentially lethal human disease. Other poxvirus infections cause primarily localized skin disease in humans.
4p
crazy_sms
09-05-2012
66
2
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài :Importance of disulphide bonds for vaccinia virus L1R protein function
5p
dauphong8
14-01-2012
27
2
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a Vaccinia virus recombinant
19p
dauphong8
14-01-2012
46
2
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity
8p
dauphong8
14-01-2012
33
2
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Origin-independent plasmid replication occurs in vaccinia virus cytoplasmic factories and requires all five known poxvirus replication factors
12p
dauphong8
14-01-2012
39
2
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis
6p
dauphong8
14-01-2012
35
2
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Susceptibility of different leukocyte cell types to Vaccinia virus infection
7p
dauphong8
14-01-2012
46
2
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus
14p
dauphong8
14-01-2012
41
2
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Vaccinia virus replication is not affected by APOBEC3 family members
8p
dauphong7
13-01-2012
60
5
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Analysis of vaccinia virus temperature-sensitive I7L mutants reveals two potential functional domains Megan J Moerdyk1, Chelsea M Byrd2 and Dennis E
7p
dauphong7
13-01-2012
66
4
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