Values in [α(g

The antimitotic depsipeptide dolastatin 15 was radiolabeled with tritium in its amino-terminal dolavaline residue. Dolastatin 15, although potently cytotoxic, is a relatively weak inhibitor oftubulin assembly and does not inhibit the binding ofany other ligand to tubulin. The only methodo-logy found to demonstrate an interaction between the dep-sipeptide and tubulin was Hummel–Dreyer equilibrium chromatography on Sephadex G-50 superfine. The average apparent Kd value obtained in these studies was about 30lM, with no difference observed when column size or tubulin concentration was varied....

7p tumor12 20-04-2013 50 4   Download

We have investigated the existence of a precoupled form of the distal C-ter-minal truncated cannabinoid receptor 1 (CB1-417) and heterotrimeric G proteins in a heterologous insect cell expression system. CB1-417 showed higher production levels than the full-length receptor. The production lev-els obtained in our expression system were double the values reported in the literature.

10p media19 05-03-2013 25 2   Download

Suppose that G is a locally compact abelian group, and write M(G) for the algebra of bounded, regular, complex-valued measures under convolution. A measure µ ∈ M(G) is said to be idempotent if µ ∗ µ = µ, or alternatively if µ takes only the values 0 and 1. The Cohen-Helson-Rudin idempotent theorem states that a measure µ is idempotent if and only if the set {γ ∈ G : µ(γ) = 1} belongs to the coset ring of G, 1. Introduction Let

31p dontetvui 17-01-2013 73 8   Download

We prove that in every finitely generated profinite group, every subgroup of finite index is open; this implies that the topology on such groups is determined by the algebraic structure. This is deduced from the main result about finite groups: let w be a ‘locally finite’ group word and d ∈ N. Then there exists f = f (w, d) such that in every d-generator finite group G, every element of the verbal subgroup w(G) is equal to a product of f w-values.

69p noel_noel 17-01-2013 48 7   Download

Let E be an elliptic curve over Q, let p be an ordinary prime for E, and let K be an imaginary quadratic field. Write K∞/K for the anticyclotomic Zp-extension of K and set G∞ = Gal(K∞/K). Following a construction of Section 2 of [BD1] which is recalled in Section 1, one attaches to the data (E,K, p) an anticyclotomic p-adic L-function Lp(E,K) which belongs to the Iwasawa algebra Λ := Zp[[G∞]]. This element, whose construction was inspired by a formula proved in [Gr1], is known, thanks to work of Zhang ([Zh, §1.

65p noel_noel 17-01-2013 46 5   Download

MULTIPLE SOLUTIONS FOR QUASILINEAR ELLIPTIC NEUMANN PROBLEMS IN ORLICZ-SOBOLEV SPACES NIKOLAOS HALIDIAS AND VY K. LE Received 15 October 2004 and in revised form 21 January 2005 We investigate the existence of multiple solutions to quasilinear elliptic problems containing Laplace like operators (φ-Laplacians). We are interested in Neumann boundary value problems and our main tool is Br´ zis-Nirenberg’s local linking theorem. e 1. Introduction In this paper, we consider the following elliptic problem with Neumann boundary condition, −div α ∇u(x) ∇u(x) = g(x,u) a.e. on Ω (1.1) ∂u = 0 a.e.

8p sting12 10-03-2012 27 2   Download

BOUNDARY VALUE PROBLEMS FOR ANALYTIC FUNCTIONS IN THE CLASS OF CAUCHY-TYPE INTEGRALS WITH DENSITY IN L p(·) (Γ) V. KOKILASHVILI, V. PAATASHVILI, AND S. SAMKO Received 9 July 2004 We study the Riemann boundary value problem Φ+ (t) = G(t)Φ− (t) + g(t), for analytic functions in the class of analytic functions represented by the Cauchy-type integrals with density in the spaces L p(·) (Γ) with variable exponent. We consider both the case when the coefficient G is piecewise continuous and the case when it may be of a more general nature, admitting its oscillation.

29p sting12 10-03-2012 51 9   Download

BEHAVIOR OF THE POSITIVE SOLUTIONS OF FUZZY MAX-DIFFERENCE EQUATIONS G. STEFANIDOU AND G. PAPASCHINOPOULOS Received 15 September 2004 We extend some results obtained in 1998 and 1999 by studying the periodicity of the solutions of the fuzzy difference equations xn+1 = max{A/xn ,A/xn−1 ,...,A/xn−k }, xn+1 = max{A0 /xn ,A1 /xn−1 }, where k is a positive integer, A, Ai , i = 0,1, are positive fuzzy numbers, and the initial values xi , i = −k, −k + 1,...,0 (resp., i = −1,0) of the first (resp., second) equation are positive fuzzy numbers. 1. Introduction Difference equations are often used in...

20p sting12 10-03-2012 40 4   Download

Let G be a graph with vertex set V (G) = {1, . . . , n} and edge set E(G). We are interested in studying the functions of the graph G whose values belong to the interval [(G), (G)]. Here (G) is the size of the largest stable set in G and (G) is the smallest number of cliques that cover the vertices of G. It is well known (see, for example, [1]) that for some  0 it is impossible to approximate in polynomial time (G) and (G) within a factor of n, assuming P 6= NP. We suppose that better approximation could...

5p thulanh5 12-09-2011 68 4   Download

The name “Bacillus laevolacticus” Nakayama and Yanoshi 1967 was not included on the Approved Lists of Bacterial Names and therefore has no standing in bacteriological nomenclature. In this study 22 catalasepositive, acid-tolerant, facultatively anaerobic, lactic acid-producingBacillus strains were examined taxonomically and compared with a number of strains belonging to phenetically similar Bacillus species (Bacillus coagulans, Bacillus smithii, “Bacillus vesiculiferous”) and with Sporolactobacillus. The G+ C contents (43 to 45 mol%), DNA-DNA homology values ...

6p ngovanquang12c3 18-12-2010 97 9   Download