Wheezing phenotypes

Early wheezing and asthma are relevant health problems in the tropics. Mite sensitization is an important risk factor, but the roles of others, inherent in poverty, are unknown. We designed a birth-cohort study in Cartagena (Colombia) to investigate genetic and environmental risk factors for asthma and atopy, considering as particular features perennial exposure to mites, parasite infections and poor living conditions.

15p vianthony2711 16-04-2021 5 2   Download

Most epidemiological studies on pediatric asthma rely on the report of “wheezing” in questionnaires. Our aim was to investigate the understanding of this term by parents and health professionals.

9p virubber2711 21-03-2020 8 2   Download

Infections. During infancy, a number of viruses have been associated with the inception of the asthmatic phenotype. Respiratory syncytial virus (RSV) and parainfluenza virus produce a pattern of symptoms including bronchiolitis that parallel many features of childhood asthma53,54. A number of long-term prospective studies of children admitted to the hospital with documented RSV have shown that approximately 40% will continue to wheeze or have asthma into later childhood53.

17p dacotaikhoan 26-04-2013 47 2   Download