World irreversibly

The irreversible epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) afatinib and dac‑ omitinib are approved for first-line treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC). We aimed to compare the efficacy and safety of afatinib and dacomitinib in this setting.

11p vikoch 27-06-2024 1 1   Download

The purpose of the study was to find out the possibilities of adapting states to global trends in the digital transformation of the main spheres of life for survival and development in an emerging multi-polar world. The work was done as part of a grant from the Russian Foundation for Basic Research and discloses the results of the initial stage of its implementation. Our task was to develop a conceptual vision for solving the problems of adapting states to global trends in digital transformation and to justify the mechanisms for its implementation in practice.

6p longtimenosee04 06-03-2024 2 1   Download

Ripening is the final stage in the life cycle of a fruit and it is an irreversible process. During ripening, fruits undergo various physiological and biochemical changes. These changes includes conversion of sugar from one form to another, textural changes, colour changes, change in aroma and flavor. Banana is one of the most easily available climacteric fruit which is distributed throughout the world. Since it is a climacteric fruit, its commercial ripening can be carried out in storage houses to obtain good flavor, proper texture and uniform peel colour.

6p chauchaungayxua11 23-03-2021 17 1   Download

Biochar is essentially fine-grained charcoal applied to soils, which is being promoted primarily for climate change mitigation and for raising soil fertility. Climate change is one of the biggest challenges facing our globalized world today. The poor population in developing countries will be particularly affected by global warming, of which developed countries are the major drivers. Science clearly indicates that a global temperature rise of 2°C above pre-industrial levels may change the face of the world irreversibly.

8p nguaconbaynhay6 24-06-2020 8 0   Download

Malnutrition is still public health problem in some parts of the world and causes irreversible damage at infant stage. Infants require high energy and nutrient dense foods because of their high growth velocity. Feeding fortified complementary blended foods is one of the options to treat malnourished infants. These foods are prepared with cereallegume blend, oil, sugar, vitamin/minerals and animal source protein. Complementary foods with high sugar content (> 15%) are not recommended to treat malnourished group. Animal source protein in complementary foods leads to hike in production cost.

8p caygaocaolon5 27-05-2020 32 1   Download

Stray dog bite is one of the public health problem in the world and there is a great need of envisaging irreversible contraceptive methods in dogs. Therefore, the present study was conducted to evaluate the effects of intra epididymal zinc arginine administration in prepubertal dogs. Eighteen pre-pubertal stray community dogs weighing 6-8 kg were administered with zinc arginine solution@ 0.2 ml per each cauda epididymis percutaneously using 26 gauge, ½ inch needle.

13p angicungduoc4 26-04-2020 8 0   Download

Myopia is an important public health problem due to its prevalence and significant public health cost. Elevating levels of myopia increase the risk of vision impairment, and therefore, high myopia has become one of the main causes of untreatable vision loss throughout the world due to its irreversible complications.

5p vinasaki2711 12-11-2019 14 1   Download

The relational model is one of many ways of modeling data from the real world. The modeling process starts with the identification of the things in the real world that you are modeling. These real world things are called entities. If you were creating a database to catalog your music library, the entities would be things like compact disc, song, band, record label, and so on. Entities do not need to be tangible things; they can also be conceptual things like a genre or a concert.

31p nhacsihuytuan 13-04-2013 39 2   Download

In recent years, energy prices have become increasingly more expensive and volatile. This trend has added to auto ownership costs and uncertainty about future operating expenses. Moreover, parking in many of the world’s largest cities is limited and costly further adding to private vehicle expenditures. Many nations worldwide have adopted carsharing (or short-term auto access) as a means to reduce personal transportation costs and the negative impacts of widespread auto use including: congestion, inefficient land use, energy consumption, and emissions.

28p nhacnenzingme 23-03-2013 52 4   Download

Ouedraogo et al. 2006). Most patients presented with symptoms suspicious for TB; thus, lack of diagnostic sensitivity of health workers is of concern (Wandwalo & Morkve 2000). Afghanistan has the highest TB burden in south Asia (World Health Organization 2007). While health services are expanding and quality improving, gaps in access and deficient quality of some interventions persist. The Ministry of Public Health adopted a Basic Package of Health Services (BPHS) in 2003, which provides standard primary care services for districts covering 77% of the population.

7p taisaocothedung 12-01-2013 51 2   Download

This book contains the papers presented at the International Conference on the Management of Natural Resources, Sustainable Development and Ecological Hazards, which was held in Patagonia, Argentina. The Conference name was shortened to ‘The Ravage of the Planet’ to emphasize the urgency of the problems under discussion. The state of our planet continues to deteriorate at an alarming rate. We have arrived at a situation where we need to determine urgent solutions before we reach a point of irreversible damage....

860p camchuong_1 11-12-2012 98 13   Download

Growing numbers of governments and peoples around the world are now convinced that if nothing is done, we will adversely and irreversibly affect the earth’s climate to our own detriment. Yet even as global concern has risen, the prospect of an effective collective response is not guaranteed.

225p vantrungtran 01-02-2010 110 27   Download