Wound healing efficacy

This study is conducted to compare the repair efficacy of chitosan application on hoof lesions with the conventional treatment materials, regarding the aspects of clinical, radiographical and hematological findings. Since the puncture wounds including hoof abscess is the main cause of lameness and the difficulties in healing of hoof lesions due to difficulties in contraction and the high incidences for contamination.

19p trinhthamhodang11 27-04-2021 8 1   Download

The objective of this study was to investigate the antibacterial activity and healing efficacy of Psidium guajava leaf on an excision-wound infected with Staphylococcus aureus using a rat model. The antibacterial activities of the methanol leaf extract alone and combinations of the plant extract with amoxicillin as well as the effect of osmotic stress were determined by using broth microdilution method. The therapeutic effect of the methanol extract was evaluated on an excision-wound infected with Staphylococcus aureus.

16p trinhthamhodang5 16-05-2020 12 1   Download

. One approach in wound dressing development is to incorporate active molecules or drugs in the dressing. In order to reduce the frequency of dressing changes as well as to prolong wound healing efficacy, wound dressings that can sustain the release of the active molecules should be developed. In our previous work, we developed chitosan/sericin (CH/SS) microspheres that released sericin in a controlled rate. However, the difficulty of applying the microspheres that easily diffuse and quickly degrade onto the wound was its limitations.

12p caothientrangnguyen 09-05-2020 11 0   Download

The Clerodendrum infortunatiom Linn (CI) is one of the most important medicinal plant containing different properties like anti-inflammatory activities, anti-microbial activities, wound healing, promotes neo-vascularisation, and reduces oxidative stress. The present study was undertaken to evaluate the wound healing activity of hydro-alcoholic (70% ethanol) leaves extract of C. infortunatum Linn as 4 % ointment in cutaneous wound model in diabetic rats.

13p kethamoi4 16-04-2020 12 2   Download

In the study, we fabricated a thermosensitive nanocomposite hydrogel, which incorporated dual active curcumin and chitosan. Beside of a well-known characteristic of chitosan for wound healing, curcumin has been a lot of interest in burn wound healing application due to ability in depleting the action of oxidative radicals and stimulation of fibroblast cells. In order to enhance the therapeutic efficacy of curcumin, we introduced a new method to synthesize nanocurcumin in the thermosensitive chitosan-g-Pluronic F127 copolymer solution under ultrasonication.

10p abcxyz123_02 03-03-2020 9 1   Download

Treatment of castration-resistant prostate cancer (CRPC) patients with androgen deprivation therapy puts prostate cancer in remission while treatment with already available drugs in market including abirater one help in controlling advanced prostate cancers for sometime though fail to respond, evolve resistance mechanisms, and undergo genetic deregulations later on with poor patient survival rate and no cure.

24p nguathienthan2 26-12-2019 15 1   Download

There is no consensus on the properties of an ideal dressing for treating wounds. The aim of this study was to investigate the efficacy of dressings using topically administered bitter melon extract with olive oil, pure olive oil, nitrofurazone, and saline in the healing of ischemic wounds.

11p nutifooddau 27-01-2019 26 1   Download