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Zebrafish’ embryo
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Part 1 book "Insights from animal reproduction" includes content: Cryopreservation of sheep produced embryos – current and future perspectives, assisted reproductive techniques on south american wild mammals, the use of reproductive technologies to produce transgenic goats, major components in limiting litter size, germ cell determinant transmission, segregation, and function in the zebrafish embryo.
145p
muasambanhan02
25-12-2023
7
1
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Trim-Away is a recent technique to rapidly deplete a protein from any cell type. Guided by antibodies, TRIM21 selects proteins for destruction. However, the applicability of this method in model organisms has not been investigated. Here, we show that Trim-Away can degrade proteins in zebrafish embryos.
6p
vigalileogalilei
27-02-2022
13
1
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This study investigates the pesticides atrazine, chlorpyrifos, and dieldrin for endocrine disrupting, phenotypic, and neurobehavioral effects. Zebrafish embryos were exposed to various environmentally relevant concentrations of pesticides during two critical windows, 0-5 days post fertilization (dpf) throughout embryogenesis and 4- 5 dpf at early larval development.
12p
thebadguys
15-01-2022
10
0
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In this study, we sampled 6 types of cigarettes: ThangLong, Vina, Craven, Demi, Maxx and Bastos from local stores and conducted toxicological tests on zebrafish larvae. Our results show that there are variations in toxicological properties of total particle matter collected from different cigarette brands in lethal and morphological effects on zebrafish embryos.
7p
meyerowitz
25-12-2021
8
0
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In this study, three alkaloid fractions from Huperzia serrata (Thunb.) Trevis, Lycopodium clavatum L. and Huperzia squarrosa (G. Forst.) Trevis were tested in two toxicity models: mouse primary neuronal cell (in vitro) and zebrafish (Danio rerio) embryos (in vivo).
9p
guitaracoustic02
08-12-2021
15
1
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Reprogramming histone modification patterns to coordinate gene expression in early zebrafish embryos
Multicellular organisms require precise gene regulation during ontogeny, and epigenetic modifications, such as DNA methylation and histone modification, facilitate this precise regulation. The conservative reprogramming patterns of DNA methylation in vertebrates have been well described.
13p
visilicon2711
20-08-2021
8
1
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Genetic studies in mouse have demonstrated the crucial function of PAX4 in pancreatic cell differentiation. This transcription factor specifies β- and δ-cell fate at the expense of α-cell identity by repressing Arx gene expression and ectopic expression of PAX4 in α-cells is sufficient to convert them into β-cells.
16p
vimariana2711
22-12-2020
7
0
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Primary cilia are essential for Hedgehog (Hh) signal transduction in vertebrates. Although the core components of the Hh pathway are highly conserved, the dependency on cilia in Hh signaling is considered to be lower in fish than in mice, suggesting the presence of species-specific mechanisms for Hh signal transduction.
11p
viwyoming2711
16-12-2020
12
1
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Tbx5 deficiency in zebrafish causes several abnormal phenotypes of the heart and pectoral fins. It has been reported that exogenous human growth hormone can enhance expression of downstream mediators in the growth hormone and insulin-like growth factor I (IGF-I) pathway and partially restore dysmorphogenesis in tbx5 morphants.
15p
viwyoming2711
16-12-2020
13
1
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C-lectin family 14 Member A (Clec14a) is a transmembrane protein specifically expressed in vascular endothelial cells during embryogenesis. Previous in vitro and in vivo studies have provided conflicting data regarding Clec14a role in promoting or inhibiting angiogenesis, therefore its functional role in vascular development remains poorly understood.
10p
viwyoming2711
16-12-2020
9
2
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Rab proteins are GTPases responsible for intracellular vesicular trafficking regulation. Rab11 proteins, members of the Rab GTPase family, are known to regulate vesicular recycling during embryonic development. In zebrafish, there are 3 rab11 paralogues, known as rab11a, rab11ba and rab11bb, sharing high identity with each other.
8p
viwyoming2711
16-12-2020
13
1
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Zebrafish (Danio rerio) is a model organism that has emerged as a tool for cancer research, cancer being the second most common cause of death after cardiovascular disease for humans in the developed world.
12p
vibaku2711
22-07-2020
12
1
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Developmental biology relies to a large extent on the observation and comparison of phenotypic traits through time using high resolution microscopes. In this context, transparent model organisms such as the zebrafish Danio rerio in which developing tissues and organs can be easily observed and imaged using fluorescent proteins have become very popular.
10p
vihamax2711
21-04-2020
13
0
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Zebrafish embryos are emerging as a model for pharmacological and toxicological studies. We used zebrafish embryos to study the general toxicity and cardiovascular effects of eight methylxanthines: aminophylline, caffeine, diprophylline, doxofylline, etophylline, 3-isobutyl-1-methylxanthine (IBMX), pentoxifylline and theophylline.
12p
vimax2711
30-03-2020
23
2
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The cardiotoxicity of isoniazid on zebrafish embryos and its underlying mechanism is unclear. Methods: Here, we exposed zebrafish embryos at 4 h post-fertilization to different levels of isoniazid and recorded the morphology and number of malformed and dead embryos under the microscope.
9p
vimax2711
27-03-2020
47
2
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The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice and zebrafish embryos) models. Overall, the results obtained are promising.
11p
trinhthamhodang1
14-11-2019
18
1
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This study investigated the developmental toxicity of zinc chloride (ZnCl2) in zebrafish embryos (Brachydanio rerio, Cyprinidae, Cypriniformes). Zebrafish embryos were exposed to 5 different concentrations of ZnCl2, from the blastula stage, for 15 days under static renewal test conditions.
7p
vivant2711
01-02-2019
15
2
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Nghiên cứu được tiến hành nhằm đánh giá tác động của ion đồng (Cu2+) ở các nồng độ 0µg/L; 500 µg/L; 1000 µg/L; 2000 µg/L lên các hoạt động sinh lí trong giai đoạn phôi của cá Ngựa vằn (Danio rerio Hamilton, 1822). Để nắm nội dung mời các bạn cùng tham khảo.
8p
danhvi10
22-11-2018
28
2
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We have determined the structure of the fatty acid-binding protein 6 (fabp6) gene and the tissue-specific distribution of its transcripts in embryos, larvae and adult zebrafish (Danio rerio). Like most members of the vertebrate FABPmultigene family, the zebrafishfabp6 gene contains four exons separated by three introns.
10p
galaxyss3
07-03-2013
34
2
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There are two hatching enzyme homologues in the zebrafish genome: zebrafish hatching enzymeZHE1andZHE2. Northern blot and RT-PCR analysis revealed that ZHE1 was mainly expressed in pre-hatching embryos, whereasZHE2was rarely expressed. This was consistent with the results obtained in an experiment conducted at the protein level, which demonstrated that one kind of hatching enzyme, ZHE1, was able to be purified from the hatching liquid.
13p
vinaphone15
28-02-2013
52
1
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