The past thirty years have witnessed the birth, growth, and evolution of clinical electrophysiology from a field whose initial goals were the understanding of arrhythmia
mechanisms to one of significant therapeutic impact. The development and refinement of implantable devices and catheter ablation have made non-pharmacologic
therapy a treatment of choice for most arrhythmias encountered in clinical practice.
The historical route to present-day patch clamping started with the
scientific recognition that electrical phenomena are part of animal physiology.
This bioelectricity was demonstrated in the nineteenth century in
frogs, where muscle movements could be evoked by applying electrical
stimuli to the animal. The recording of inherent electrical activity can be
charted by the development of increasingly sophisticated electrodes.
Not Otherwise Specified [NOS]). We also review functional brain
imaging studies of patients with various forms of conversion disorder (e.g. psychogenic
motor or sensory changes, psychogenic blindness, pseudoseizures) as well as
depersonalization disorder. As hypnotizability traits have been postulated to be associated
with a higher tendency for developing dissociative symptoms, we briefly refer to functional
imaging studies of hypnosis.
The neurosciences have experienced tremendous and wonderful progress in many areas, and the spectrum encompassing the neurosciences is expansive. Suffice it to mention a few classical fields: electrophysiology, genetics, physics, computer sciences, and more recently, social and marketing neurosciences. Of course, this large growth resulted in the production of many books.
There is value in minimally invasive investigations for ‘difficult’ pains, such as bone scans, MRI, CT and
electrophysiological testing. There is a need for clear information on what pain services can provide and how they
may be accessed. Better links between palliative care and specialist pain services are also important.
Care of a patient suffering from cancer pain requires a holistic approach combining psychological support, social
support, rehabilitation and pain management in order to provide the best possible quality of life or quality of