Aberrant GSTP1 promoter methylation is associated with increased risk and advanced stage of breast cancer: A metaanalysis of 19 case-control studies

Glutathione S-transferase P1 (GSTP1) has been reported to function as a tumor suppressor gene in various types of human cancers. Aberrant methylation of tumor-related genes at the promoter regions can inactivate genes, which is important in the carcinogenesis of breast cancer.