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Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: A rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies

Chia sẻ: ViHamax2711 ViHamax2711 | Ngày: | Loại File: PDF | Số trang:17

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There is an ever-increasing need of monoclonal antibodies (mAbs) for biomedical applications and fully human binders are particularly desirable due to their reduced immunogenicity in patients.

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Nội dung Text: Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: A rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies

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