Association of serum bone- and musclederived factors with age, sex, body composition, and physical function in community-dwelling middle-aged and elderly adults: A cross-sectional study

Understanding interactions between bone and muscle based on endocrine factors may help elucidate the relationship between osteoporosis and sarcopenia. However, whether the abundance or activity of these endocrine factors is affected by age and sex or whether these factors play a causal role in bone and muscle formation and function is unclear.