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Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana
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This work proposes a model of the metabolic branch-point between the methionine and threonine biosynthesis path-ways inArabidopsis thalianawhich involves kinetic compe-tition for phosphohomoserine between the allosteric enzyme threonine synthase and the two-substrate enzyme cysta-thionine c-synthase. Threonine synthase is activated by S-adenosylmethionine and inhibited by AMP. Cystathio-ninec-synthase condenses phosphohomoserine to cysteine via a ping-pong mechanism.
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