intTypePromotion=1

Báo cáo khoa học: Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP–caspase interaction

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:13

0
25
lượt xem
2
download

Báo cáo khoa học: Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP–caspase interaction

Mô tả tài liệu
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

Previous results have shown that the human oncoembryonic proteina-feto-protein (AFP) induces dose-dependent targeting apoptosis in tumor cells, accompanied by cytochromecrelease and caspase 3 activation. AFP posi-tively regulates cytochrome c⁄dATP-mediated apoptosome complex forma-tion in a cell-free system, stimulates release of the active caspases 9 and 3 and displaces cIAP-2 from the apoptosome and from its complex with recombinant caspases 3 and 9 [Semenkova et al. (2003) Eur. J. Biochem.

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP–caspase interaction

ADSENSE
ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2