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Báo cáo khoa học: Aly⁄ REF, a factor for mRNA transport, activates RH gene promoter function

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:0

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The rhesus (Rh) blood group antigens are of considerable importance in transfusion medicine as well as in newborn or autoimmune hemolytic diseases due to their high antigenicity. We identified a major DNaseI hypersensitive site at the 5¢ flanking regions of bothRHDandRHCEexon 1. A 34 bp fragment located at)191 to)158 from a translation start posi-tion, and containing the TCCCCTCCC sequence, was involved in enhan-cing promoter activity, which was assessed by luciferase reporter gene assay.

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Nội dung Text: Báo cáo khoa học: Aly⁄ REF, a factor for mRNA transport, activates RH gene promoter function

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