Báo cáo khóa học: Assembly of the silk fibroin elementary unit in endoplasmic reticulum and a role of L-chain for protection of a1,2-mannose residues in N-linked oligosaccharide chains of fibrohexamerin/P25
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Silk fibroin ofBombyx moriis secreted from the posterior silkgland (PSG) as a2.3-MDa elementaryunit, consistingof six sets of a disulfide-linked heavy chain (H-chain)–light chain (L-chain) heterodimer and one molecule of fibrohex-amerin (fhx)/P25. Fhx/P25, a glycoprotein, associates non-covalently with the H–L heterodimers. The elementary unit was found and purified from the endoplasmic reticulum (ER) extract of PSG cells.
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