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Báo cáo khoa học: Cellular and molecular action of the mitogenic protein-deamidating toxin from Pasteurella multocida
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The mitogenic toxin fromPasteurella multocida(PMT) is a member of the dermonecrotic toxin family, which includes toxins fromBordetella, Escheri-chia coliandYersinia. Members of the dermonecrotic toxin family modu-late G-protein targets in host cells through selective deamidation and⁄or transglutamination of a critical active site Gln residue in the G-protein tar-get, which results in the activation of intrinsic GTPase activity.
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