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Báo cáo khoa học: Characterization of scorpion a-like toxin group using two new toxins from the scorpion Leiurus quinquestriatus hebraeus

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:14

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Two novel toxins, Lqh6 andLqh7, isolated from the venom of the scorpionLeiurus quinquestriatus hebraeus,have in their sequence amolecular signature (8Q/KPE10) associated with a recently defined group ofa-toxins that target Na channels, namely thea-like toxins [reviewed inGordon, D., Savarin, P.,Gurevitz,M.&Zinn-Justin, S. (1998)J. Toxicol. Toxin Rev.17, 131–159]. Lqh6 and Lqh7 are highly toxic to insects and mice, and inhibit the binding of a-toxins to cockroach neuronal membranes.

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Nội dung Text: Báo cáo khoa học: Characterization of scorpion a-like toxin group using two new toxins from the scorpion Leiurus quinquestriatus hebraeus

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