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báo cáo khoa hoc : Construction and humanization of a functional bispecific EGFR · CD16 diabody using a refolding system

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

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We previously reported the construction and activity of a humanized, bispecific diabody (hEx3) that recruited T cells towards an epidermal growth factor receptor (EGFR) positive tumor. Herein, we describe the construction of a second functional, fully humanized, anti-EGFR bispecific diabody that recruits another subset of lymphocyte effectors, the natural killer cells, to EGFR-expressing tumor cells.

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Nội dung Text: báo cáo khoa hoc : Construction and humanization of a functional bispecific EGFR · CD16 diabody using a refolding system

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