intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

36
lượt xem
2
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

An arti®cial peroxidase-like hemoprotein has been obtained by associating a monoclonal antibody, 13G10, and its iron(III)±a,a,a,b-meso-tetrakis(ortho-carboxyphenyl)por-phyrin [Fe(ToCPP)] hapten. In this antibody, about two-thirds of the porphyrinmoiety is inserted in the binding site, its ortho-COOH substituents being recognized by amino-acids of the protein, and a carboxylic acid side chain of the protein acts as a general acid base catalyst in the heterolytic cleavage of the O±O bond of H2O2, but no amino-acid res-idue is actingas anaxial ligandof the iron....

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2