intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

45
lượt xem
5
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

The mitochondrial cytochromeb missense mutation, G167E, has been reported inapatientwithcardiomyopathy. The residue G167 is located in an extramembranous helix close to the hinge region of the iron–sulfur protein. In order to characterize the effects of the mutation on the structure and function of thebc1complex, we introducedG167E into the highly similar yeast cytochromeb. The mutation had a severe effect on the respiratory function, with the activity of thebc1complex decreased to a fewper cent of the wild type....

Chủ đề:
Lưu

Nội dung Text: Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2